Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL194998 | 0.81 | POLB (0.49) | POLBGAAGFERMAPTHPGD | |
| SCHEMBL7904417 | 0.80 | POLB (0.47) | POLBGAAGFERMAPTHPGD | |
| SCHEMBL3709507 | 0.80 | POLB (0.48) | POLBGAAGFERMAPTHPGD | |
| SCHEMBL12425507 | 0.76 | POLB (0.56) | POLBGAAGFERMAPTHPGD | |
| SCHEMBL5014668 | 0.75 | POLB (0.59) | POLBGAAGFERMAPTHPGD | |
| SCHEMBL3714416 | 0.74 | CA1 (0.43) | SMN1; SMN2MEN1KMT2ALPAR1LMNA | |
| SCHEMBL20969580 | 0.72 | TAAR1 (0.57) | POLBGAAGFERCYP1A2HTR2C | |
| SCHEMBL7193138 | 0.70 | POLB (0.44) | POLBGAAGFERMAPTHPGD | |
| SCHEMBL14036774 | 0.69 | GAA (0.51) | POLBGAAGFERMAPTHPGD | |
| SCHEMBL26551435 | 0.69 | POLB (0.56) | POLBGAAGFERMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010098488-A1 | ARYL IMIDAZOLE COMPOUNDS AND THEIR USE AS BETA AMYLOID PRODUCTION INHIBITORS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-09-02 | — | — | WO | disclosed |