Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7904417 | 0.84 | POLB (0.47) | POLBGAAGFERLPAR1KDM4E | |
| SCHEMBL194998 | 0.82 | POLB (0.49) | POLBGAAGFERLPAR1KDM4E | |
| SCHEMBL3709735 | 0.80 | POLB (0.47) | POLBGAAGFERLPAR1KDM4E | |
| SCHEMBL12425507 | 0.77 | POLB (0.56) | POLBGAAGFERKDM4EMAPT | |
| SCHEMBL14036774 | 0.76 | GAA (0.51) | POLBGAAGFERKDM4EMAPT | |
| SCHEMBL5014668 | 0.76 | POLB (0.59) | POLBGAAGFERMAPTHPGD | |
| SCHEMBL20969580 | 0.73 | TAAR1 (0.57) | POLBGAAGFER | |
| SCHEMBL28118962 | 0.72 | CTSD (0.50) | POLBGAAGFERKDM4EMAPT | |
| SCHEMBL14036621 | 0.71 | MEN1 (0.49) | POLBGAAGFERKDM4EMAPT | |
| SCHEMBL5013641 | 0.71 | POLB (0.43) | POLBGAAGFERLPAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010098488-A1 | ARYL IMIDAZOLE COMPOUNDS AND THEIR USE AS BETA AMYLOID PRODUCTION INHIBITORS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-09-02 | — | — | WO | disclosed |
| WO-2010098488-A1 | ARYL IMIDAZOLE COMPOUNDS AND THEIR USE AS BETA AMYLOID PRODUCTION INHIBITORS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-09-02 | — | — | WO | disclosed |