Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.40 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20969580 | 0.86 | TAAR1 (0.57) | POLBGAAGFERTAAR1HTR2A | |
| SCHEMBL12425507 | 0.84 | POLB (0.56) | POLBGAAGFERTAAR1MEN1 | |
| SCHEMBL14036774 | 0.79 | GAA (0.51) | POLBGAAGFERMEN1ALDH1A1 | |
| SCHEMBL6852792 | 0.78 | POLB (0.68) | POLBGAAGFERMEN1ALDH1A1 | |
| SCHEMBL11079472 | 0.78 | POLB (0.50) | POLBGAAGFERTAAR1MEN1 | |
| SCHEMBL194998 | 0.77 | POLB (0.49) | POLBGAAGFERMEN1ALDH1A1 | |
| SCHEMBL14295929 | 0.77 | POLB (0.66) | POLBGAAGFERMEN1ALDH1A1 | |
| Thymoquinol Dimethylether SCHEMBL12613923 | 0.77 | POLB (0.66) | POLBGAAGFERTAAR1MEN1 | |
| SCHEMBL7904417 | 0.76 | POLB (0.47) | POLBGAAGFERMEN1ALDH1A1 | |
| SCHEMBL3709507 | 0.76 | POLB (0.48) | POLBGAAGFERMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008137102-A2 | METHODS OF MODULATING AMYLOID BETA AND COMPOUNDS USEFUL THEREFOR | TORREYPINES THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |
| WO-2008137102-A2 | METHODS OF MODULATING AMYLOID BETA AND COMPOUNDS USEFUL THEREFOR | TORREYPINES THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |