Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 17/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7032122 | 0.88 | GRIA4 (0.42) | GRIA4GRIA1GRIA2GRIA3 | |
| SCHEMBL3828099 | 0.86 | TAAR1 (0.47) | GRIA4 | |
| SCHEMBL15663101 | 0.84 | GRIA4 (0.62) | GRIA4 | |
| SCHEMBL6940515 | 0.81 | MAPT (0.51) | GRIA4 | |
| SCHEMBL6936033 | 0.77 | CA1 (0.48) | — | |
| SCHEMBL6749856 | 0.76 | CA1 (0.43) | — | |
| SCHEMBL28938093 | 0.75 | SLC22A12 (0.38) | — | |
| SCHEMBL28938091 | 0.75 | SLC22A12 (0.38) | — | |
| SCHEMBL21295131 | 0.73 | PNMT (0.47) | — | |
| SCHEMBL30601282 | 0.70 | CA1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010087982-A1 | GLUR2 RECEPTOR MODULATORS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2010-08-05 | — | — | WO | disclosed |