Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | XDH | P47989 | 4/20 | 0.47 |
| ▸ | THRB | P10828 | 4/20 | 0.45 |
| ▸ | THRA | P10827 | 3/20 | 0.45 |
| ▸ | ICMT | O60725 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3714294 | 0.90 | CDC7 (0.45) | RAB9AXDHTHRBTHRAICMT | |
| SCHEMBL3707571 | 0.88 | RAB9A (0.55) | RAB9AXDHTHRBTHRAKDM4E | |
| SCHEMBL3703608 | 0.85 | RAB9A (0.52) | RAB9AXDHTHRBTHRAICMT | |
| SCHEMBL3718086 | 0.84 | RAB9A (0.53) | RAB9AXDHTHRBTHRAKDM4E | |
| SCHEMBL3715308 | 0.84 | XDH (0.64) | RAB9AXDHTHRBTHRAKDM4E | |
| SCHEMBL3712098 | 0.83 | RAB9A (0.58) | RAB9AXDHTHRBTHRAKDM4E | |
| SCHEMBL3713673 | 0.83 | XDH (0.67) | XDH | |
| SCHEMBL3713653 | 0.81 | RAB9A (0.49) | RAB9AXDHTHRBTHRAKDM4E | |
| SCHEMBL3710951 | 0.80 | XDH (0.56) | RAB9AXDHTHRBTHRAKDM4E | |
| SCHEMBL3712007 | 0.80 | XDH (0.61) | RAB9AXDHTHRBTHRAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | claimed |
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |