Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 2/20 | 0.35 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3713666 | 0.90 | CYP19A1 (0.39) | FNTAFNTBFFAR1ADORA3ADORA1 | |
| SCHEMBL13188334 | 0.88 | HDAC6 (0.43) | ADORA3ADORA1ADORA2AMEN1RAB9A | |
| SCHEMBL13188263 | 0.85 | HDAC6 (0.42) | FFAR1HIF1AEPAS1ALDH1A1XIAP | |
| SCHEMBL3714241 | 0.84 | HDAC6 (0.41) | FFAR1HIF1AEPAS1ALDH1A1MEN1 | |
| SCHEMBL3721264 | 0.84 | FFAR1 (0.37) | FFAR1ADORA1HIF1AEPAS1ALDH1A1 | |
| SCHEMBL3716099 | 0.84 | FFAR1 (0.41) | FFAR1HIF1AEPAS1KDM4EALDH1A1 | |
| SCHEMBL3714333 | 0.83 | HDAC1 (0.49) | ADORA3ADORA1HIF1AEPAS1ALDH1A1 | |
| SCHEMBL3720871 | 0.83 | CLK2 (0.37) | FFAR1ADORA3ADORA1ADORA2AHIF1A | |
| SCHEMBL3719635 | 0.83 | ABL1 (0.41) | — | |
| SCHEMBL3709347 | 0.81 | PTGES (0.42) | HIF1AEPAS1ALDH1A1XIAPBIRC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |