Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3714241 | 0.90 | HDAC6 (0.41) | — | |
| SCHEMBL3711909 | 0.89 | PIK3CG (0.42) | ABL1 | |
| SCHEMBL3714104 | 0.89 | ABL1 (0.41) | ABL1 | |
| SCHEMBL13188356 | 0.88 | ABL1 (0.52) | ABL1 | |
| SCHEMBL3709347 | 0.87 | PTGES (0.42) | — | |
| SCHEMBL3711250 | 0.87 | TSHR (0.42) | — | |
| SCHEMBL3714333 | 0.85 | HDAC1 (0.49) | ABL1 | |
| SCHEMBL13188263 | 0.85 | HDAC6 (0.42) | — | |
| SCHEMBL3717280 | 0.85 | ROCK2 (0.48) | — | |
| SCHEMBL3709438 | 0.83 | HIF1A (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |