Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 6/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 2/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3707303 | 0.78 | HTT (0.36) | HTTSMN1; SMN2PARP1 | |
| SCHEMBL3704905 | 0.72 | CYP19A1 (0.44) | FBP1XDHAPEX1 | |
| SCHEMBL3710221 | 0.68 | FBP1 (0.47) | FBP1XDH | |
| SCHEMBL3031133 | 0.66 | GRIN2D (0.46) | FBP1XDHHRH4MAPTLMNA | |
| SCHEMBL28471005 | 0.65 | FBP1 (1.00) | FBP1XDHHRH4MAPTAPEX1 | |
| SCHEMBL27787935 | 0.65 | FBP1 (0.42) | FBP1ALOX15ALOX12XDHHRH4 | |
| SCHEMBL3710296 | 0.63 | FBP1 (0.40) | FBP1HRH4TDP1 | |
| SCHEMBL17865690 | 0.62 | HRH4 (0.49) | FBP1XDHHRH4MAPTLMNA | |
| SCHEMBL30849043 | 0.62 | FBP1 (0.46) | FBP1XDHHRH4MAPTAPEX1 | |
| SCHEMBL27237581 | 0.62 | FBP1 (0.46) | FBP1XDHHRH4MAPTAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |