Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 2/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | TPMT | P51580 | 2/20 | 0.35 |
| ▸ | EIF4A3 | P38919 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3708249 | 0.87 | LMNA (0.37) | FBP1KDM4EHRH4 | |
| SCHEMBL3707303 | 0.82 | HTT (0.36) | — | |
| SCHEMBL23684463 | 0.75 | GPR84 (0.43) | FBP1TTRTPMTTSHRKDM4E | |
| SCHEMBL7920912 | 0.75 | TTR (0.46) | TTRTPMTTSHRPLAUHRH4 | |
| SCHEMBL3534704 | 0.75 | DAO (0.49) | TTRTPMTEIF4A3TSHRKDM4E | |
| SCHEMBL3707995 | 0.74 | RAB9A (0.47) | TSHRKDM4E | |
| SCHEMBL8553610 | 0.71 | CASP3 (0.50) | EIF4A3PLAUKDM4EGRIN2DGRIN2A | |
| SCHEMBL31695109 | 0.70 | TPMT (0.41) | TTRTPMTKDM4EHRH4TDP1 | |
| SCHEMBL15592243 | 0.67 | TTR (0.43) | TTRTPMTEIF4A3TSHRPLAU | |
| SCHEMBL400398 | 0.66 | TSHR (0.53) | TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |