⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL93576 | 1.00 | — | — | |
| SCHEMBL6070950 | 1.00 | — | — | |
| SCHEMBL2541475 | 0.82 | CA2 (0.30) | — | |
| SCHEMBL10777932 | 0.78 | — | — | |
| SCHEMBL14690105 | 0.78 | — | — | |
| SCHEMBL19097311 | 0.77 | CA2 (0.30) | — | |
| SCHEMBL5690410 | 0.77 | TDP1 (0.33) | — | |
| Hexanoate SCHEMBL28220317 | 0.76 | AKR1B1 (0.44) | — | |
| SCHEMBL367023 | 0.76 | — | — | |
| SCHEMBL2257240 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2740458-B1 | Packaging comprising forms of sodium salt of 4-tert-butyl-N-[4-chloro-2-(1-oxy-pyridine-4-carbonyl)-phenyl]-benzenesulfonamide | IP GES FÜR MAN MBH (DE) | 2016-08-03 | — | — | EP | disclosed |
| WO-2010097350-A1 | A PROCESS FOR THE PREPARATION OF AN ALDEHYDE BETA-LACTAM COMPOUND | ADAMED SP. Z O.O. (PL) | 2010-09-02 | — | — | WO | disclosed |
| US-7560575-B2 | Process for preparation of racemic Nebivolol | ACINO PHARMA AG (CH) | 2009-07-14 | — | — | US | disclosed |
| US-20070149612-A1 | Process for preparation of racemic Nebivolol | ACINO PHARMA AG (CH) | 2007-06-28 | — | — | US | disclosed |
| US-20060116400-A1 | Oxazolidinone and/or isoxazoline derivatives as antibacterial agents | ASTRAZENECA AB (SE) | 2006-06-01 | — | — | US | disclosed |
| EP-1567532-A1 | OXAZOLIDINONE AND / OR ISOXAZOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | Astrazeneca AB (SE) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004048392-A1 | OXAZOLIDINONE AND / OR ISOXAZOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2004-06-10 | — | — | WO | disclosed |