Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.78 |
| ▸ | FAAH | O00519 | 1/20 | 0.78 |
| ▸ | MAPT | P10636 | 1/20 | 0.78 |
| ▸ | HPGD | P15428 | 1/20 | 0.78 |
| ▸ | CNR1 | P21554 | 1/20 | 0.78 |
| ▸ | CNR2 | P34972 | 1/20 | 0.78 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.69 |
| ▸ | PRKCA | P17252 | 2/20 | 0.69 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.69 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.69 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.69 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11895706 | 1.00 | ALDH1A1 (0.78) | ALDH1A1FAAHMAPTHPGDCNR1 | |
| SCHEMBL1008217 | 1.00 | ALDH1A1 (0.78) | ALDH1A1FAAHMAPTHPGDCNR1 | |
| SCHEMBL1008969 | 1.00 | ALDH1A1 (0.78) | ALDH1A1FAAHMAPTHPGDCNR1 | |
| SCHEMBL10492005 | 0.97 | ALDH1A1 (0.74) | ALDH1A1FAAHMAPTHPGDCNR1 | |
| SCHEMBL10492058 | 0.94 | ALDH1A1 (0.69) | ALDH1A1FAAHMAPTHPGDCNR1 | |
| SCHEMBL2520687 | 0.94 | PRKCA (0.78) | ALDH1A1FAAHMAPTHPGDCNR1 | |
| SCHEMBL9754681 | 0.94 | PRKCA (0.78) | ALDH1A1FAAHMAPTHPGDCNR1 | |
| SCHEMBL10491979 | 0.94 | PRKCA (0.78) | ALDH1A1FAAHMAPTHPGDCNR1 | |
| SCHEMBL22558535 | 0.94 | PRKCA (0.78) | ALDH1A1FAAHMAPTHPGDCNR1 | |
| SCHEMBL9754687 | 0.94 | PRKCA (0.78) | ALDH1A1FAAHMAPTHPGDCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10092599-B2 | Methods for enhancing hematopoietic stem/progenitor cell engraftment | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2018-10-09 | — | — | US | claimed |
| US-20150246075-A1 | METHODS FOR ENHANCING HEMATOPOIETIC STEM/PROGENITOR CELL ENGRAFTMENT | CHILDREN'S MEDICAL CENTER CORPORATION | 2015-09-03 | — | — | US | claimed |
| WO-2010096264-A2 | METHODS FOR ENHANCING HEMATOPOIETIC STEM/PROGENITOR CELL ENGRAFTMENT | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2010-08-26 | — | — | WO | claimed |
| US-20240150719-A1 | MAGNETIC SHEAR BIOREACTOR APPARATUS AND METHODS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2024-05-09 | — | — | US | disclosed |
| EP-4294919-A1 | MAGNETIC SHEAR BIOREACTOR APPARATUS AND METHODS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-12-27 | — | — | EP | disclosed |
| EP-3313982-B1 | METHODS AND APPARATUS FOR CONDITIONING CELL POPULATIONS FOR CELL THERAPIES | UNIV TEXAS (US) | 2023-09-13 | — | — | EP | disclosed |
| WO-2022178357-A1 | MAGNETIC DESCRIPTION MAGNETIC SHEAR BIOREACTOR APPARATUS AND METHODS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2022-08-25 | — | — | WO | disclosed |
| CN-114561277-A | Methods and devices for conditioning cell populations for cell therapy | 得克萨斯州大学系统董事会 | 2022-05-31 | — | — | CN | disclosed |
| CN-107849523-B | Methods and devices for conditioning cell populations for cell therapy | 得克萨斯州大学系统董事会 | 2021-12-10 | — | — | CN | disclosed |
| US-10669516-B2 | Methods and apparatus for conditioning cell populations for cell therapies | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2020-06-02 | — | — | US | disclosed |
| US-10092599-B2 | Methods for enhancing hematopoietic stem/progenitor cell engraftment | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2018-10-09 | — | — | US | disclosed |
| US-20180187141-A1 | METHODS AND APPARATUS FOR CONDITIONING CELL POPULATIONS FOR CELL THERAPIES | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2018-07-05 | — | — | US | disclosed |
| US-20150246075-A1 | METHODS FOR ENHANCING HEMATOPOIETIC STEM/PROGENITOR CELL ENGRAFTMENT | CHILDREN'S MEDICAL CENTER CORPORATION | 2015-09-03 | — | — | US | disclosed |
| US-9056085-B2 | Methods for enhancing hematopoietic stem/progenitor cell engraftment | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2015-06-16 | — | — | US | disclosed |
| US-20120195862-A1 | BIOMECHANICAL INDUCTION OF HEMATOPOIESIS | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2012-08-02 | — | — | US | disclosed |
| WO-2010096264-A2 | METHODS FOR ENHANCING HEMATOPOIETIC STEM/PROGENITOR CELL ENGRAFTMENT | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2010-08-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150246075-A1 | METHODS FOR ENHANCING HEMATOPOIETIC STEM/PROGENITOR CELL ENGRAFTMENT | HCLS1, MCL1, THPO | ALDH1A1 92/4885FAAH 3539/4885MAPT 4738/4885 |
| US-10092599-B2 | Methods for enhancing hematopoietic stem/progenitor cell engraftment | HCLS1, MCL1, THPO | ALDH1A1 92/4885FAAH 3539/4885MAPT 4738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.