Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CCND3 | P30281 | 1/20 | 0.52 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1074961 | 0.85 | ALDH1A1 (0.56) | TSHRCCND3CDK6RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29381203 | 0.84 | RAB9A (0.54) | TSHRCCND3CDK6RAB9ASMN1; SMN2 | |
| SCHEMBL1892162 | 0.84 | RAB9A (0.54) | TSHRCCND3CDK6RAB9ASMN1; SMN2 | |
| SCHEMBL5320628 | 0.83 | TSHR (0.54) | TSHRRAB9ASMN1; SMN2ATMMEN1 | |
| SCHEMBL1897467 | 0.82 | MAPT (0.56) | TSHRCCND3CDK6RAB9ASMN1; SMN2 | |
| SCHEMBL7438275 | 0.82 | CCND3 (0.44) | TSHRCCND3CDK6RAB9ASMN1; SMN2 | |
| SCHEMBL10141202 | 0.81 | — | — | |
| SCHEMBL21114388 | 0.81 | TSHR (0.57) | TSHRRAB9ASMN1; SMN2CYP2D6CYP1A2 | |
| SCHEMBL302811 | 0.81 | — | — | |
| SCHEMBL28298 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 259 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111072796-B | Pyrrolone photoinitiation system and application | 北京化工大学 | 2021-05-11 | — | — | CN | claimed |
| CN-111072796-A | Pyrrolone photoinitiation system and application | 北京化工大学 | 2020-04-28 | — | — | CN | claimed |
| CN-105052946-B | A kind of Herbicidal combinations of grass containing azole ketones and topramezone | 河南远见农业科技有限公司 | 2018-01-02 | — | — | CN | claimed |
| CN-107011320-A | Cyclopropyl substituted thiophene naphthenic amine compound and application thereof | 广州医科大学 | 2017-08-04 | — | — | CN | claimed |
| US-20130245033-A1 | AMIDE COMPOUNDS | GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2013-09-19 | — | — | US | claimed |
| EP-2509949-A2 | PYRIDINONE HYDROXYCYCLOPENTYL CARBOXAMIDES: HIV INTEGRASE INHIBITORS WITH THERAPEUTIC APPLICATIONS | University Of Georgia Research Foundation, Inc. (US) | 2012-10-17 | — | — | EP | claimed |
| WO-2011071849-A2 | PYRIDINONE HYDROXYCYCLOPENTYL CARBOXAMIDES: HIV INTEGRASE INHIBITORS WITH THERAPEUTIC APPLICATIONS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2011-06-16 | — | — | WO | claimed |
| CN-101300345-A | Aggrecanase structure | WYETH CORP (US) | 2008-11-05 | — | — | CN | claimed |
| CN-1880303-A | substituted pyrrolidone synthesized ion liquid and its synthesis method | UNIV GUANGDONG TECHNOLOGY (CN) | 2006-12-20 | — | — | CN | claimed |
| US-20030167965-A1 | Single cartridge magenta and color ink-jet set | EVERLIGHT USA, INC. (US) | 2003-09-11 | — | — | US | claimed |
| EP-0159584-A2 | N-(azolylcarbamoyl)-hydroxyl amines and fungicides containing them | BASF Aktiengesellschaft (DE) | 1985-10-30 | — | — | EP | claimed |
| EP-0156255-A2 | N-((2,3-dihydrobenzofuran)-2-yl)-azolyl ureas and fungicides containing them | BASF Aktiengesellschaft (DE) | 1985-10-02 | — | — | EP | claimed |
| EP-0065107-B1 | AZOLYLPROPYL-OXIMINO DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION AS FUNGICIDES AND GROWTH REGULATOR FOR PLANTS | BAYER AG (DE) | 1985-09-18 | — | — | EP | claimed |
| EP-0047405-B1 | AZOLYLALKYL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | BAYER AG (DE) | 1984-06-20 | — | — | EP | claimed |
| EP-0108995-A1 | Hydroxyalkinyl-azolyl derivatives | BAYER AG (DE) | 1984-05-23 | — | — | EP | claimed |
| EP-0100952-A1 | Substituted azolylallyl ketones and carbinols | BAYER AG (DE) | 1984-02-22 | — | — | EP | claimed |
| EP-0097881-A2 | Substituted azolyl ketones and alcohols | BAYER AG (DE) | 1984-01-11 | — | — | EP | claimed |
| EP-0096786-A2 | Hydroxyalkynyl-azolyl derivatives, process for their preparation and their use as fungicides | BAYER AG (DE) | 1983-12-28 | — | — | EP | claimed |
| EP-0065107-A2 | Azolylpropyl-oximino derivatives, process for their preparation and their application as fungicides and growth regulator for plants | BAYER AG (DE) | 1982-11-24 | — | — | EP | claimed |
| EP-0007505-A2 | Alpha-azolyl-beta-hydroxy-ketones, process for their preparation and their use as fungicides | BAYER AG (DE) | 1980-02-06 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130245033-A1 | AMIDE COMPOUNDS | AR, AVPR2, H1-0 | TSHR 125/4885CCND3 935/4885CDK6 1892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.