Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.31 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.31 |
| ▸ | PI4KA | P42356 | 1/20 | 0.31 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.31 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3626407 | 0.78 | ALDH1A1 (0.38) | ALDH1A1HSD17B10RXFP1SMN1; SMN2NPC1 | |
| SCHEMBL361017 | 0.76 | ALDH1A1 (0.39) | ALDH1A1HSD17B10RXFP1SMN1; SMN2NPC1 | |
| SCHEMBL4238924 | 0.75 | PIK3CD (0.48) | ALDH1A1HSD17B10RXFP1SMN1; SMN2HTT | |
| SCHEMBL734395 | 0.69 | ALDH1A1 (0.72) | ALDH1A1HSD17B10RXFP1SMN1; SMN2NPC1 | |
| SCHEMBL12912394 | 0.67 | ALDH1A1 (0.56) | ALDH1A1HSD17B10RXFP1SMN1; SMN2NPC1 | |
| SCHEMBL939004 | 0.67 | ALDH1A1 (0.47) | ALDH1A1HSD17B10RXFP1SMN1; SMN2LMNA | |
| SCHEMBL1703918 | 0.66 | PIK3CD (0.58) | ALDH1A1HSD17B10RXFP1SMN1; SMN2HTT | |
| SCHEMBL12912404 | 0.66 | ALDH1A1 (0.51) | ALDH1A1HSD17B10RXFP1SMN1; SMN2HTT | |
| SCHEMBL20409291 | 0.66 | ALDH1A1 (0.61) | ALDH1A1HSD17B10RXFP1SMN1; SMN2LMNA | |
| SCHEMBL735173 | 0.65 | PIK3CG (0.51) | ALDH1A1HSD17B10RXFP1LMNAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009452-A1 | THE ROLE OF P13K P110 DELTA SIGNALING IN RETROVIRAL INFECTION AND REPLICATION | PHILADELPHIA HEALTH & EDUCATION CORPORATION (US) | 2012-01-19 | — | — | WO | claimed |