Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.52 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.52 |
| ▸ | THRA | P10827 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 3/20 | 0.40 |
| ▸ | USP10 | Q14694 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 2/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7883332 | 0.84 | CDC7 (0.56) | CDC7DBF4MAPTRAB9AGABRA1 | |
| SCHEMBL3709678 | 0.84 | CDC7 (0.56) | CDC7DBF4MAPTRAB9AGABRA1 | |
| SCHEMBL3704380 | 0.82 | CDC7 (0.51) | CDC7DBF4THRATHRBMAPT | |
| SCHEMBL3708608 | 0.81 | CDC7 (0.53) | CDC7DBF4GABRA1GABRB2IMPDH2 | |
| SCHEMBL2822552 | 0.78 | CDC7 (0.68) | CDC7DBF4MAPTGAARAB9A | |
| SCHEMBL3708038 | 0.77 | CDC7 (0.48) | CDC7DBF4THRATHRBUSP10 | |
| SCHEMBL3711151 | 0.76 | CDC7 (0.59) | CDC7DBF4 | |
| SCHEMBL1647788 | 0.72 | ALDH1A1 (0.41) | MAPTRAB9AGABRA1GABRB2 | |
| SCHEMBL23794795 | 0.72 | CDC7 (0.79) | CDC7DBF4MAPTRAB9A | |
| SCHEMBL16456794 | 0.71 | CDC7 (0.77) | CDC7DBF4MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |