SCHEMBL3711010

SCHEMBL3711010

O=C(Nc1cccc(-c2ccncc2)c1)[C@H](Cc1ccccc1)NCCCc1ccccn1

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR142 Q7Z601 19/20 0.64
KMT2A Q03164 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3716298 0.94 GPR142 (0.69) GPR142KMT2A
SCHEMBL3712523 0.85 GPR142 (0.64) GPR142
SCHEMBL3715637 0.82 GPR142 (0.83) GPR142
SCHEMBL2684020 0.81 GPR142 (0.68) GPR142
SCHEMBL2684015 0.81 GPR142 (0.68) GPR142
SCHEMBL6029395 0.79 GPR142 (0.57) GPR142KMT2A
SCHEMBL2685195 0.78 GPR142 (1.00) GPR142
SCHEMBL2685198 0.78 GPR142 (1.00) GPR142
SCHEMBL2684914 0.77 GPR142 (0.80) GPR142
SCHEMBL2684917 0.77 GPR142 (0.80) GPR142

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010093849-A2 PHENYLALANINE AMIDE DERIVATIVES USEFUL FOR TREATING INSULIN-RELATED DISEASES AND CONDITIONS AMGEN INC. (US) 2010-08-19 WO disclosed