SCHEMBL3715637

SCHEMBL3715637

O=C(Nc1cccc(-c2ccncc2)c1)[C@H](Cc1ccccc1)NCCc1cscn1

nearest known ligand 0.83

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR142 Q7Z601 20/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2685198 0.91 GPR142 (1.00) GPR142
SCHEMBL2685195 0.91 GPR142 (1.00) GPR142
SCHEMBL3716298 0.88 GPR142 (0.69) GPR142
Trifluoroacetic Acid SCHEMBL2686389 0.86 GPR142 (0.91) GPR142
SCHEMBL6028653 0.86 GPR142 (1.00) GPR142
SCHEMBL3712523 0.86 GPR142 (0.64) GPR142
SCHEMBL2684664 0.83 GPR142 (0.70) GPR142
SCHEMBL3711010 0.82 GPR142 (0.64) GPR142
SCHEMBL6032243 0.81 GPR142 (0.89) GPR142
SCHEMBL6032428 0.81 GPR142 (1.00) GPR142

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010093849-A2 PHENYLALANINE AMIDE DERIVATIVES USEFUL FOR TREATING INSULIN-RELATED DISEASES AND CONDITIONS AMGEN INC. (US) 2010-08-19 WO disclosed