Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3712947 | 0.89 | GPR119 (0.49) | GPR119POLBNPBWR1MCHR1 | |
| SCHEMBL3711023 | 0.83 | GPR119 (0.42) | GPR119KDM4E | |
| SCHEMBL3805418 | 0.83 | KDM1A (0.53) | GPR119POLBKDM4E | |
| SCHEMBL1634644 | 0.82 | NPBWR1 (0.52) | GPR119NPBWR1MCHR1 | |
| SCHEMBL3720713 | 0.82 | PDE4A (0.48) | GPR119POLB | |
| SCHEMBL3055131 | 0.81 | GPR119 (0.47) | GPR119POLB | |
| SCHEMBL2630824 | 0.81 | GPR119 (0.54) | GPR119POLB | |
| SCHEMBL18318684 | 0.79 | GPR119 (0.48) | GPR119KDM4E | |
| SCHEMBL18319181 | 0.78 | GPR119 (0.49) | GPR119 | |
| SCHEMBL18318437 | 0.78 | CHEK2 (0.49) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010094643-A1 | QUINOLINE DERIVATIVES AND THEIR USES FOR RHINITIS AND URTICARIA | GLAXO GROUP LIMITED (GB) | 2010-08-26 | — | — | WO | disclosed |