Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13188651 | 0.93 | SMN1; SMN2 (0.53) | MAPK1SMN1; SMN2BDKRB1KMT2A | |
| SCHEMBL3709590 | 0.91 | HIF1A (0.43) | MAPK1SMN1; SMN2BDKRB1 | |
| SCHEMBL3714327 | 0.86 | KMT2A (0.50) | MAPK1SMN1; SMN2BDKRB1KMT2A | |
| SCHEMBL3712170 | 0.83 | MAPK1 (0.52) | MAPK1SMN1; SMN2KMT2AMMP2MMP8 | |
| SCHEMBL254974 | 0.81 | MAPK1 (0.70) | MAPK1SMN1; SMN2KMT2AMMP2MMP8 | |
| SCHEMBL3715041 | 0.80 | HDAC1 (0.52) | MAPK1SMN1; SMN2KMT2A | |
| SCHEMBL13188642 | 0.79 | KMT2A (0.54) | MAPK1SMN1; SMN2BDKRB1KMT2A | |
| SCHEMBL3715178 | 0.78 | KMT2A (0.49) | KMT2AMMP2MMP8MMP13 | |
| SCHEMBL3720699 | 0.78 | MAPK1 (0.47) | MAPK1SMN1; SMN2MMP2MMP8MMP13 | |
| SCHEMBL3717935 | 0.77 | MAPK1 (0.50) | MAPK1SMN1; SMN2KMT2AMMP2MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |