Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AIMP2 | Q13155 | 1/20 | 0.39 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.37 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.37 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 4/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13188471 | 0.92 | GRM5 (0.39) | AIMP2PRKD1PRKD2ACACBGRM5 | |
| SCHEMBL3713715 | 0.92 | CYP19A1 (0.40) | CYP19A1CYP11B1CYP11B2ACACBGRM5 | |
| SCHEMBL3713383 | 0.90 | CYP19A1 (0.39) | CYP19A1CYP11B1CYP11B2ACACBGRM5 | |
| SCHEMBL13187826 | 0.89 | CYP11B1 (0.46) | AIMP2DGAT2PRKD1PRKD2CYP19A1 | |
| SCHEMBL3711841 | 0.89 | CYP19A1 (0.42) | PRKD1PRKD2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL3711913 | 0.88 | CYP19A1 (0.41) | PRKD1PRKD2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL3712077 | 0.87 | ABL1 (0.39) | CYP19A1CYP11B1CYP11B2GRM5PIM1 | |
| SCHEMBL3711200 | 0.87 | PRKD1 (0.41) | PRKD1PRKD2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL3714045 | 0.85 | CYP19A1 (0.41) | CYP19A1CYP11B1CYP11B2GRM5SLC2A1 | |
| SCHEMBL3709548 | 0.84 | ALDH1A1 (0.42) | PRKD1PRKD2CYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |