SCHEMBL3711376

SCHEMBL3711376

CCCCCCCCC=CCCCCCCCC(=O)C(O)CN(CCCN(C)C)C(=O)CCCCCCCC=CCCCCCCCC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ EPHX2 P34913 4/20 0.48
▸ CNR1 P21554 1/20 0.45
▸ FFAR1 O14842 1/20 0.42
▸ FFAR4 Q5NUL3 1/20 0.42
▸ TERT O14746 2/20 0.42
▸ GMNN O75496 1/20 0.42
▸ USP2 O75604 1/20 0.42
▸ LMNA P02545 1/20 0.42
▸ CYP1A2 P05177 1/20 0.42
▸ POLB P06746 1/20 0.42
▸ MAPT P10636 1/20 0.42
▸ CYP2C9 P11712 1/20 0.42
▸ ALOX15 P16050 1/20 0.42
▸ APEX1 P27695 1/20 0.42
▸ CYP2C19 P33261 1/20 0.42
▸ RECQL P46063 1/20 0.42
▸ BLM P54132 1/20 0.42
▸ NPSR1 Q6W5P4 1/20 0.42
▸ HSD17B10 Q99714 1/20 0.42
▸ DUSP3 P51452 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL8726596 0.96 EPHX2 (0.48) EPHX2CNR1FFAR1FFAR4TERT
SCHEMBL9275665 0.92 DNM1 (0.43) —
SCHEMBL29234726 0.81 CES2 (0.44) FFAR1FFAR4
SCHEMBL8697480 0.81 CNR1 (0.57) EPHX2CNR1TERTGMNNUSP2
SCHEMBL28310308 0.81 CNR1 (0.57) EPHX2CNR1TERTGMNNUSP2
SCHEMBL158055 0.80 EPHX2 (0.58) EPHX2CNR1TERTGMNNUSP2
SCHEMBL14661022 0.80 EPHX2 (0.58) EPHX2CNR1TERTGMNNUSP2
SCHEMBL158058 0.80 EPHX2 (0.58) EPHX2CNR1TERTGMNNUSP2
SCHEMBL8483146 0.80 DNM1 (0.46) FFAR1FFAR4
SCHEMBL13498748 0.80 EPHX2 (0.58) EPHX2CNR1TERTGMNNUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0523189-A4 — VICAL INC (US) 1995-04-26 — — EP claimed
EP-0523189-A1 CATIONIC LIPIDS FOR INTRACELLULAR DELIVERY OF BIOLOGICALLY ACTIVE MOLECULES VICAL, INC. (US) 1993-01-20 — — EP claimed
WO-1991016024-A1 CATIONIC LIPIDS FOR INTRACELLULAR DELIVERY OF BIOLOGICALLY ACTIVE MOLECULES VICAL, INC. (US) 1991-10-31 — — WO claimed
EP-2231190-A1 PARTICULATE DRUG CARRIERS AS DESENSITIZING AGENTS Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. (IL) 2010-09-29 — — EP disclosed
EP-2125011-A2 STIMULATION OF AN IMMUNE RESPONSE BY CATIONIC LIPIDS PDS Biotechnology Corporation (US) 2009-12-02 — — EP disclosed
WO-2009072136-A1 PARTICULATE DRUG CARRIERS AS DESENSITIZING AGENTS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2009-06-11 — — WO disclosed
WO-2008116078-A9 STIMULATION OF AN IMMUNE RESPONSE BY CATIONIC LIPIDS PDS BIOTECHNOLOGY CORP (US) 2008-11-20 — — WO disclosed
WO-2008116078-A2 STIMULATION OF AN IMMUNE RESPONSE BY CATIONIC LIPIDS PDS BIOTECHNOLOGY CORPORATION (US) 2008-09-25 — — WO disclosed
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