SCHEMBL371177

SCHEMBL371177

CCCCCCCCCCCCCCCCOC(P)C(CO)OC(=O)CCCCCCCCCCCCCCC

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.55
MAPK1 P28482 1/20 0.55
LMNA P02545 4/20 0.50
PRKCA P17252 4/20 0.49
PRKCE Q02156 2/20 0.49
PRKCQ Q04759 2/20 0.49
PRKCD Q05655 2/20 0.49
ALDH1A1 P00352 1/20 0.45
DGKA P23743 1/20 0.45
KDM4E B2RXH2 1/20 0.44
DUSP3 P51452 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
DNM1 Q05193 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1273212 0.92 PRKCA (0.55) MAPTMAPK1PRKCAPRKCEPRKCQ
SCHEMBL368664 0.88 MAPT (0.62) MAPTMAPK1LMNAPRKCAPRKCE
SCHEMBL369749 0.88 MAPT (0.62) MAPTMAPK1LMNAPRKCAPRKCE
SCHEMBL367858 0.88 MAPT (0.62) MAPTMAPK1LMNAPRKCAPRKCE
SCHEMBL9958966 0.88 MAPT (0.62) MAPTMAPK1LMNAPRKCAPRKCE
SCHEMBL16612763 0.82 MAPT (0.72) MAPTMAPK1LMNAPRKCAPRKCE
SCHEMBL16612232 0.82 MAPT (0.72) MAPTMAPK1LMNAPRKCAPRKCE
SCHEMBL1273757 0.81 PRKCA (0.55) MAPTMAPK1PRKCAPRKCEPRKCQ
SCHEMBL370806 0.81 USP2 (0.43) MAPTLMNAALDH1A1MEN1KMT2A
SCHEMBL369784 0.80 PRKCA (0.60) MAPTMAPK1PRKCAPRKCEPRKCQ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4384612-A1 IMPROVED METHOD FOR SMALL RNA PURIFICATION Mirnagreen S.r.l. (IT) 2024-06-19 EP disclosed
CN-111867634-B Enhancement of translocation of micro/nanoparticles across mucus layers using alginate oligomers 阿尔吉法玛公司 2024-06-11 CN disclosed
CN-117940563-A Improved small RNA purification process 米尔纳格林有限责任公司 2024-04-26 CN disclosed
WO-2023017116-A1 IMPROVED METHOD FOR SMALL RNA PURIFICATION MIRNAGREEN S.R.L. (IT) 2023-02-16 WO disclosed
EP-4134432-A1 IMPROVED METHOD FOR SMALL RNA PURIFICATION Mirnagreen S.r.l. (IT) 2023-02-15 EP disclosed
CN-114729336-A Cell-free composition for ATP regeneration and use thereof 百奥堪引赛股份有限公司 2022-07-08 CN disclosed
US-20220204967-A1 METHODS FOR EXTRACTING BIOACTIVE SMALL RNAS FROM PLANTS AND MUSHROOMS MIRNAGREEN S.R.L. (IT) 2022-06-30 US disclosed
US-20220145282-A1 Cell-Free Compositions for ATP Regeneration and Uses Thereof BIOCHEMINSIGHTS, INC. 2022-05-12 US disclosed
EP-3924471-A1 CELL-FREE COMPOSITIONS FOR ATP REGENERATION AND USES THEREOF Biocheminsights Inc. (US) 2021-12-22 EP disclosed
EP-3901259-A1 METHODS FOR EXTRACTING BIOACTIVE SMALL RNAS FROM PLANTS AND MUSHROOMS Mirnagreen S.r.l. (IT) 2021-10-27 EP disclosed
US-20130251630-A1 Entrapment of Radionuclides in Nanoparticle Compositions RIGSHOSPITALET (DK) 2013-09-26 US disclosed
WO-2013135800-A1 CATIONIC LIPOSOMAL DRUG DELIVERY SYSTEM FOR SPECIFIC TARGETING OF HUMAN CD14+ MONOCYTES IN WHOLE BLOOD BIONEER A/S (DK) 2013-09-19 WO disclosed
EP-2638896-A1 Cationic liposomal drug delivery system for specific targeting of human cd14+ monocytes in whole blood Bioneer A/S (DK) 2013-09-18 EP disclosed
US-20130204121-A1 NANOPARTICLE-GUIDED RADIOTHERAPY TECHNICAL UNIVERSITY OF DENMARK (DK) 2013-08-08 US disclosed
EP-2593186-A1 NANOPARTICLE-GUIDED RADIOTHERAPY Technical University of Denmark (DK) 2013-05-22 EP disclosed
US-20120213698-A1 LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE CONTAINING NANOPARTICLES RIGSHOSPITALET (DK) 2012-08-23 US disclosed
WO-2012079582-A1 ENTRAPMENT OF RADIONUCLIDES IN NANOPARTICLE COMPOSITIONS TECHNICAL UNIVERSITY OF DENMARK (DK) 2012-06-21 WO disclosed
EP-2453927-A1 LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE AND IONOPHORE CONTAINING LIPOSOMES IN WHICH THE IONOPHORE IS 2-HYDROXYQUIONOLINE (CARBOSTYRIL) OR STRUCTURALLY RELATED 2-HYDROXYQUINOLINES Technical University of Denmark (DK) 2012-05-23 EP disclosed
WO-2012007567-A1 NANOPARTICLE-GUIDED RADIOTHERAPY TECHNICAL UNIVERSITY OF DENMARK (DK) 2012-01-19 WO disclosed
WO-2011006510-A1 LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE AND IONOPHORE CONTAINING LIPOSOMES IN WHICH THE IONOPHORE IS 2-HYDROXYQUIONOLINE (CARBOSTYRIL) OR STRUCTURALLY RELATED 2-HYDROXYQUINOLINES TECHNICAL UNIVERSITY OF DENMARK (DK) 2011-01-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120213698-A1 LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE CONTAINING NANOPARTICLES LIPG, NPC1L1, CD47 MAPT 4367/4885MAPK1 4844/4885LMNA 891/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.