Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | OXTR | P30559 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 7/20 | 0.32 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7894548 | 1.00 | OPRD1 (0.32) | OPRD1OPRM1OPRK1OPRL1OXTR | |
| SCHEMBL7894823 | 0.86 | — | — | |
| SCHEMBL3707977 | 0.86 | — | — | |
| SCHEMBL7894825 | 0.86 | — | — | |
| SCHEMBL4177209 | 0.82 | SLC6A9 (0.36) | SLC6A9SLC6A5 | |
| SCHEMBL3707332 | 0.82 | SLC6A9 (0.36) | SLC6A9SLC6A5 | |
| SCHEMBL4177205 | 0.82 | SLC6A9 (0.36) | SLC6A9SLC6A5 | |
| SCHEMBL4185907 | 0.80 | SLC6A9 (0.36) | OPRD1SLC6A9SLC6A5 | |
| SCHEMBL4186222 | 0.80 | SLC6A9 (0.36) | OPRD1SLC6A9SLC6A5 | |
| SCHEMBL4185911 | 0.80 | SLC6A9 (0.36) | OPRD1SLC6A9SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010087761-A1 | 2-AZA-BICYCLO[2.2.2]OCTANE COMPOUNDS AND USES THEREOF | ASTRAZENECA AB (SE) | 2010-08-05 | — | — | WO | disclosed |