Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | VNN1 | O95497 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.42 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7888040 | 1.00 | FPR2 (0.50) | FPR2MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL7891812 | 1.00 | FPR2 (0.50) | FPR2MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL1441557 | 0.96 | FPR2 (0.49) | FPR2MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL1441554 | 0.96 | FPR2 (0.49) | FPR2MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL24710446 | 0.95 | FPR2 (0.48) | FPR2MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL21201857 | 0.93 | VNN1 (0.50) | FPR2MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL15803012 | 0.91 | FPR2 (0.46) | FPR2MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL22720334 | 0.91 | FPR2 (0.46) | FPR2MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL2674657 | 0.89 | FPR2 (0.44) | FPR2MAPTVNN1HPGDKDM5A | |
| SCHEMBL24710899 | 0.86 | FPR2 (0.48) | FPR2MAPTMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117480162-A | Compounds for the treatment or prophylaxis of PRMT5 mediated diseases | 阿古诺治疗有限公司 | 2024-01-30 | — | — | CN | disclosed |
| WO-2022258986-A1 | COMPOUNDS USEFUL IN THE TREATMENT OR PREVENTION OF A PRMT5-MEDIATED DISORDER | Argonaut Therapeutics Limited (GB) | 2022-12-15 | — | — | WO | disclosed |
| WO-2010091721-A1 | 3 -SUBSTITUTED 1-ARYLSULFONYLPIPERIDINE DERIVATIVES FOR THE TREATMENT OF PAIN | GLAXO GROUP LIMITED (GB) | 2010-08-19 | — | — | WO | disclosed |
| WO-2010091721-A1 | 3 -SUBSTITUTED 1-ARYLSULFONYLPIPERIDINE DERIVATIVES FOR THE TREATMENT OF PAIN | GLAXO GROUP LIMITED (GB) | 2010-08-19 | — | — | WO | disclosed |