Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 5/20 | 0.47 |
| ▸ | DBF4 | Q9UBU7 | 5/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3705829 | 0.99 | CDC7 (0.47) | CDC7DBF4TRPM8MAPTKDM4E | |
| SCHEMBL3713403 | 0.88 | CDC7 (0.44) | CDC7DBF4TRPM8MAPTKDM4E | |
| SCHEMBL3706147 | 0.88 | RAB9A (0.49) | KDM4EALDH1A1 | |
| SCHEMBL3714301 | 0.87 | RAB9A (0.50) | KDM4EALDH1A1 | |
| SCHEMBL3706016 | 0.86 | XDH (0.52) | CDC7DBF4KDM4EALDH1A1 | |
| SCHEMBL3709450 | 0.84 | XDH (0.52) | CDC7DBF4KDM4EALDH1A1 | |
| SCHEMBL7891290 | 0.82 | CDC7 (0.45) | CDC7DBF4TRPM8MAPTKDM4E | |
| SCHEMBL3712069 | 0.82 | XDH (0.54) | CDC7DBF4TRPM8KDM4EALDH1A1 | |
| SCHEMBL3705195 | 0.81 | CDC7 (0.46) | CDC7DBF4TRPM8MAPTKDM4E | |
| SCHEMBL3713956 | 0.81 | CDC7 (0.51) | CDC7DBF4TRPM8MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |