Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 4/20 | 0.38 |
| ▸ | PLG | P00747 | 3/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4740640 | 0.79 | HCAR3 (0.55) | MAPK14EPHX2PPARGHCAR3MAPK11 | |
| SCHEMBL7873400 | 0.78 | SLC9A1 (0.46) | — | |
| Hydrochloric Acid SCHEMBL7880715 | 0.77 | SLC9A1 (0.46) | — | |
| SCHEMBL16595470 | 0.76 | HCAR3 (0.42) | MAPK14EPHX2PPARGHCAR3MAPK11 | |
| SCHEMBL28265716 | 0.75 | MAPK14 (0.39) | MAPK14EPHX2PPARGHCAR3MAPK11 | |
| SCHEMBL7880047 | 0.75 | KDM4E (0.49) | HTTMAPK14EPHX2PPARGMAPK11 | |
| SCHEMBL23658023 | 0.74 | PLAU (0.51) | PLAUPLGASH1LSMN1; SMN2 | |
| SCHEMBL3481264 | 0.74 | PRKCI (0.58) | MAPK14PRKCI | |
| SCHEMBL21244767 | 0.74 | KDM4E (0.39) | MAPK14SMN1; SMN2 | |
| SCHEMBL23054216 | 0.74 | TP53 (0.46) | MAPK14MAOBEPHX2PPARGMAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |