Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGCG | Q16739 | 17/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 15/20 | 0.54 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3805632 | 0.90 | UGCG (0.55) | UGCGCYP3A4P2RX7 | |
| SCHEMBL3711255 | 0.87 | UGCG (0.54) | UGCGCYP3A4P2RX7ALDH1A1 | |
| SCHEMBL13260316 | 0.77 | UGCG (0.48) | UGCGCYP3A4 | |
| SCHEMBL13260406 | 0.75 | UGCG (0.56) | UGCGCYP3A4ALDH1A1 | |
| SCHEMBL13260342 | 0.74 | UGCG (0.75) | UGCGCYP3A4 | |
| SCHEMBL3709194 | 0.74 | UGCG (0.69) | UGCGCYP3A4 | |
| SCHEMBL3715484 | 0.74 | UGCG (0.69) | UGCGCYP3A4 | |
| SCHEMBL13260997 | 0.74 | UGCG (0.68) | UGCGCYP3A4ALDH1A1 | |
| SCHEMBL13261008 | 0.71 | UGCG (0.55) | UGCGCYP3A4P2RX7ALDH1A1 | |
| SCHEMBL13260989 | 0.71 | UGCG (0.70) | UGCGCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010091164-A1 | INHIBITORS OF GLUCOSYLCERAMIDE SYNTHASE | EXELIXIS, INC. (US) | 2010-08-12 | — | — | WO | disclosed |