Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.63 |
| ▸ | CES1 | P23141 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | PARP1 | P09874 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.51 |
| ▸ | WNT3A | P56704 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29368006 | 1.00 | CES2 (0.63) | CES2CES1MEN1KMT2AKDM4E | |
| SCHEMBL29987428 | 0.85 | MEN1 (0.72) | CES2CES1MEN1KMT2AKDM4E | |
| SCHEMBL12235278 | 0.84 | TDP1 (0.48) | CES1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL29772245 | 0.83 | CES2 (0.63) | CES2CES1MEN1KMT2AKDM4E | |
| SCHEMBL364308 | 0.83 | CES2 (0.63) | CES2CES1MEN1KMT2AKDM4E | |
| SCHEMBL4368509 | 0.82 | CES2 (0.61) | CES2CES1MEN1KMT2AKDM4E | |
| SCHEMBL16619526 | 0.82 | CES2 (0.61) | CES2CES1MEN1KMT2AKDM4E | |
| SCHEMBL633161 | 0.82 | CES2 (0.61) | CES2CES1MEN1KMT2AKDM4E | |
| SCHEMBL13785097 | 0.82 | CES2 (0.61) | CES2CES1MEN1KMT2AKDM4E | |
| SCHEMBL2294919 | 0.82 | PARP1 (0.62) | CES2CES1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 214 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118924749-A | Preparation method of chromone amide compound for Alzheimer disease drug | 广西民族大学 | 2024-11-12 | — | — | CN | claimed |
| CN-117778281-A | Recombinant genetic engineering bacterium and preparation method of (R) -2- (1-aminoethyl) -4-fluorophenol | 爱斯特（成都）生物制药股份有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-114751870-B | 2- (isoxazole-5-yl) phenyl-3, 4-dihydroxybenzoate and derivative thereof, and synthetic method and application thereof | 贵州医科大学 | 2023-10-20 | — | — | CN | claimed |
| CN-116790686-A | Method for synthesizing (R) -2- (1-aminoethyl) -4-fluorophenol by biological enzyme method | 中国科学院青岛生物能源与过程研究所 | 2023-09-22 | — | — | CN | claimed |
| CN-112973606-B | Stirring device for preparing 5-fluoro-2-hydroxyacetophenone | 河南科锐化工有限公司 | 2023-07-07 | — | — | CN | claimed |
| CN-115302917-A | Metal surface phenolic foam sandwich board for building | 山东北理华海复合材料有限公司 | 2022-11-08 | — | — | CN | claimed |
| CN-114751870-A | 2- (isoxazole-5-yl) phenyl-3, 4-dihydroxy benzoate and derivative thereof, and synthesis method and application thereof | 贵州医科大学 | 2022-07-15 | — | — | CN | claimed |
| CN-114539042-A | Novel synthesis process of 5-fluoro-2-hydroxyacetophenone | 河南旭瑞新材料科技有限公司 | 2022-05-27 | — | — | CN | claimed |
| CN-107586796-B | Synthesis method of (R) -2- (1-aminoethyl) -4-fluorophenol | 暨明医药科技（苏州）有限公司 | 2021-08-06 | — | — | CN | claimed |
| CN-113045398-A | Preparation process of 5-fluoro-2-hydroxyacetophenone | 河南科锐化工有限公司 | 2021-06-29 | — | — | CN | claimed |
| CN-112973606-A | Stirring device for preparing 5-fluoro-2-hydroxyacetophenone | 河南科锐化工有限公司 | 2021-06-18 | — | — | CN | claimed |
| WO-2021020998-A1 | METHOD FOR PRODUCING ROXADUSTAT | ФАЗЫЛОВ, Марат Феликсович | 2021-02-04 | — | — | WO | claimed |
| CN-102311417-B | Method for preparing benzodihydropyran compound | CHENGDU HONGDA PHARMACEUTICAL CO LTD | 2013-09-18 | — | — | CN | claimed |
| CN-102557909-A | Preparation method for 5-fluorin-2-hydroxyacetophenone | SHANGHAI SINOFLUORO SCIENT CO | 2012-07-11 | — | — | CN | claimed |
| CN-102344431-A | Method for preparing nebivolol hydrochloride | CHENGDU KANGHONG PHARMACEUTICAL GROUP CO LTD | 2012-02-08 | — | — | CN | claimed |
| CN-102311417-A | Method for preparing benzodihydropyran compound | CHENGDU HONGDA PHARMACEUTICAL CO LTD | 2012-01-11 | — | — | CN | claimed |
| CN-102311418-A | Preparation method for benzodihydropyran compound | CHENGDU KANGHONG PHARMACEUTICALS GROUP CO LTD | 2012-01-11 | — | — | CN | claimed |
| JP-3017076-A | — | — | None | — | — | JP | disclosed |
| EP-0020018-A1 | Chroman derivatives, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1980-12-10 | — | — | EP | disclosed |
| US-4002423-A | Benzofuran derivatives process for their preparation and their use as optical brighteners | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-01-11 | — | — | US | disclosed |