Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MPI | P34949 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3711023 | 0.89 | GPR119 (0.42) | GPR119GAAATMKDM4EALDH1A1 | |
| SCHEMBL3712947 | 0.83 | GPR119 (0.49) | GPR119PIK3CD | |
| SCHEMBL18318910 | 0.82 | GPR119 (0.45) | GPR119GAAATMKDM4EALDH1A1 | |
| SCHEMBL3709889 | 0.82 | GPR119 (0.45) | GPR119TLR9TLR8TLR7HRH1 | |
| Hydrochloric Acid SCHEMBL18318133 | 0.81 | GPR119 (0.44) | GPR119GAAATMKDM4EALDH1A1 | |
| SCHEMBL3708950 | 0.80 | GPR119 (0.45) | GPR119HRH1 | |
| SCHEMBL3651433 | 0.79 | HRH1 (0.44) | GPR119HRH1 | |
| SCHEMBL3648875 | 0.79 | HRH1 (0.46) | GPR119HRH1SLC6A15 | |
| SCHEMBL3711292 | 0.78 | HRH1 (0.51) | HRH1 | |
| SCHEMBL3720029 | 0.78 | KDM4E (0.45) | GPR119KDM4ELMNAMAPTPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010094643-A1 | QUINOLINE DERIVATIVES AND THEIR USES FOR RHINITIS AND URTICARIA | GLAXO GROUP LIMITED (GB) | 2010-08-26 | — | — | WO | disclosed |