SCHEMBL3712992

SCHEMBL3712992

CC(CC(C)Pc1ccccc1)Pc1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 7/20 0.34
SLC6A2 P23975 3/20 0.34
SLC6A3 Q01959 3/20 0.34
SLC6A4 P31645 2/20 0.34
SIGMAR1 Q99720 2/20 0.34
MAOA P21397 1/20 0.34
CYP2A6 P11509 1/20 0.34
ADORA2A P29274 1/20 0.34
ADORA1 P30542 1/20 0.34
TRPA1 O75762 3/20 0.34
CHRM2 P08172 2/20 0.33
CHRM1 P11229 2/20 0.33
ADRA1A P35348 2/20 0.33
KCNH2 Q12809 2/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2D6 P10635 2/20 0.33
HTR1A P08908 1/20 0.33
ADRA2A P08913 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
SMPD1 P17405 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30361741 0.85 HIF1A (0.35) TAAR1SLC6A2SLC6A3SLC6A4SIGMAR1
SCHEMBL7558662 0.83 LMNA (0.38) TAAR1SLC6A2SLC6A3SLC6A4SIGMAR1
SCHEMBL14467392 0.80
SCHEMBL21516482 0.79 SMN1; SMN2 (0.38) TAAR1SLC6A2SLC6A3SLC6A4SIGMAR1
SCHEMBL1504888 0.79 TAAR1 (0.31) TAAR1SLC6A2SLC6A3SLC6A4SIGMAR1
SCHEMBL13510830 0.78 ACHE (0.38) TAAR1SLC6A2MAOACYP2A6TRPA1
SCHEMBL2220314 0.76 TAAR1 (0.39) TAAR1SLC6A2SLC6A3SLC6A4SIGMAR1
SCHEMBL3914867 0.76 TDP1 (0.36) TAAR1SLC6A2SLC6A3SLC6A4SIGMAR1
SCHEMBL4242152 0.76 TDP1 (0.36) TAAR1SLC6A2SLC6A3SLC6A4SIGMAR1
SCHEMBL28241076 0.74 CSNK1E (0.39) SIGMAR1OPRM1ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010086137-A1 PROCESS FOR THE PREPARATION OF AN ALLYL ARYL ETHER BY CATALYTIC O-ALLYLATON RESOLUTION RESEARCH NEDERLAND B.V. (NL) 2010-08-05 WO claimed
EP-2213643-A1 Process for the preparation of an allyl aryl ether by catalytic o-allylation Hexion Specialty Chemicals Research Belgium S.A. (BE) 2010-08-04 EP claimed
CN-113372209-B Synthesis method of megastigmatrienone 上海烟草集团有限责任公司 2022-09-13 CN disclosed
CN-103896982-A Pincer-shaped skeleton ligand containing phosphine bond and preparation of ligand, and preparation method of Pincer-shaped organic compound QINGDAO INST BIOENERGY & BIOPROCESS TECHNOLOGY CAS 2014-07-02 CN disclosed
WO-2010086137-A1 PROCESS FOR THE PREPARATION OF AN ALLYL ARYL ETHER BY CATALYTIC O-ALLYLATON RESOLUTION RESEARCH NEDERLAND B.V. (NL) 2010-08-05 WO disclosed
EP-2213643-A1 Process for the preparation of an allyl aryl ether by catalytic o-allylation Hexion Specialty Chemicals Research Belgium S.A. (BE) 2010-08-04 EP disclosed