Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR142 | Q7Z601 | 4/20 | 0.51 |
| ▸ | WNT3A | P56704 | 10/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3710190 | 0.91 | GPR142 (0.60) | GPR142 | |
| SCHEMBL2685595 | 0.88 | GPR142 (0.52) | GPR142WNT3APIK3C3MAPK1ALOX15 | |
| SCHEMBL3714046 | 0.84 | GPR142 (0.62) | GPR142 | |
| SCHEMBL3718930 | 0.81 | GPR142 (0.53) | GPR142 | |
| SCHEMBL2684336 | 0.80 | GPR142 (0.53) | GPR142WNT3APIK3C3PSEN1PSEN2 | |
| SCHEMBL2685352 | 0.79 | GPR142 (0.48) | GPR142WNT3APIK3C3MAPK1PSEN1 | |
| SCHEMBL2686194 | 0.79 | GPR142 (0.46) | GPR142WNT3APIK3C3MAPK1PSEN1 | |
| SCHEMBL2685598 | 0.78 | GPR142 (0.57) | GPR142 | |
| SCHEMBL3720905 | 0.77 | GPR142 (0.61) | GPR142ALOX15TSHRHTTSMN1; SMN2 | |
| SCHEMBL2685800 | 0.77 | GPR142 (0.57) | GPR142WNT3AMAPK1PSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093849-A2 | PHENYLALANINE AMIDE DERIVATIVES USEFUL FOR TREATING INSULIN-RELATED DISEASES AND CONDITIONS | AMGEN INC. (US) | 2010-08-19 | — | — | WO | disclosed |