Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR142 | Q7Z601 | 18/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3710190 | 0.88 | GPR142 (0.60) | GPR142 | |
| SCHEMBL3714046 | 0.88 | GPR142 (0.62) | GPR142 | |
| SCHEMBL3713017 | 0.81 | GPR142 (0.51) | GPR142 | |
| SCHEMBL2685122 | 0.77 | GPR142 (0.79) | GPR142 | |
| SCHEMBL2685126 | 0.77 | GPR142 (0.79) | GPR142 | |
| SCHEMBL2686180 | 0.76 | GPR142 (0.65) | GPR142 | |
| SCHEMBL2686173 | 0.76 | GPR142 (0.65) | GPR142 | |
| SCHEMBL3720905 | 0.76 | GPR142 (0.61) | GPR142 | |
| SCHEMBL2684653 | 0.75 | GPR142 (0.55) | GPR142 | |
| SCHEMBL3714859 | 0.73 | GPR142 (0.61) | GPR142 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093849-A2 | PHENYLALANINE AMIDE DERIVATIVES USEFUL FOR TREATING INSULIN-RELATED DISEASES AND CONDITIONS | AMGEN INC. (US) | 2010-08-19 | — | — | WO | disclosed |