Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3717996 | 0.75 | PTP4A3 (0.46) | FFAR1KMOHAO1 | |
| SCHEMBL3709987 | 0.74 | POLB (0.45) | TSHRHPGDKDM4EHTTHSD17B10 | |
| SCHEMBL3720512 | 0.70 | FFAR1 (0.46) | KDM4EGLAALDH1A1GAAFFAR1 | |
| SCHEMBL3793712 | 0.69 | PIM1 (0.39) | FFAR1HAO1 | |
| SCHEMBL3719717 | 0.69 | MAPT (0.41) | ALDH1A1FFAR1SLC6A7MAPTSMN1; SMN2 | |
| SCHEMBL27950423 | 0.69 | FFAR1 (0.55) | KDM4EALDH1A1GAAFFAR1KMO | |
| SCHEMBL3717851 | 0.68 | ALDH1A1 (0.40) | ALDH1A1NPC1RAB9A | |
| SCHEMBL3714675 | 0.68 | PTGER4 (0.42) | FFAR1HAO1 | |
| SCHEMBL3796092 | 0.68 | DHODH (0.40) | KDM4EHTTALDH1A1LMNAFFAR1 | |
| SCHEMBL3714118 | 0.68 | HDAC6 (0.43) | ALDH1A1LMNAFFAR1HAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |