Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13188764 | 0.90 | POLB (0.50) | POLBLMNAHTTHSD17B10GPR55 | |
| SCHEMBL3710281 | 0.84 | GAA (0.43) | POLBHSD17B10PIK3CAL3MBTL1GAA | |
| SCHEMBL3713408 | 0.82 | L3MBTL1 (0.39) | POLBLMNAL3MBTL1P2RY12ALDH1A1 | |
| SCHEMBL3713386 | 0.80 | L3MBTL1 (0.46) | POLBLMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL3714882 | 0.78 | L3MBTL1 (0.49) | POLBLMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL3713958 | 0.77 | L3MBTL1 (0.42) | LMNAL3MBTL1P2RY12ALDH1A1MAPT | |
| SCHEMBL3711572 | 0.75 | MAPT (0.47) | POLBLMNAHTTHSD17B10GPR55 | |
| SCHEMBL3709302 | 0.75 | BCHE (0.44) | L3MBTL1MEN1TSHRKMT2ATP53 | |
| SCHEMBL3713050 | 0.74 | TSHR (0.44) | POLBLMNAHTTHSD17B10GPR55 | |
| SCHEMBL3714505 | 0.74 | PIK3CA (0.48) | HSD17B10MTORPIK3CAPIK3CGMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |