Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MB | P02144 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | RARG | P13631 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23728221 | 0.83 | NOX1 (0.49) | NOX1KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL23728219 | 0.83 | NOX1 (0.49) | NOX1KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL3706136 | 0.81 | SMN1; SMN2 (0.42) | NOX1SMN1; SMN2L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL3707004 | 0.80 | GRK2 (0.41) | SMN1; SMN2HTTKMT2AALDH1A1MAPT | |
| SCHEMBL18731917 | 0.73 | NOX1 (0.56) | NOX1SMN1; SMN2HTTL3MBTL1KMT2A | |
| SCHEMBL861674 | 0.72 | SMN1; SMN2 (0.84) | SMN1; SMN2HTTL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL6204592 | 0.71 | MAPT (0.67) | SMN1; SMN2HTTL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL10027943 | 0.69 | NOX1 (0.47) | NOX1SMN1; SMN2KMT2AALDH1A1MAPT | |
| SCHEMBL7490760 | 0.69 | MAPT (0.48) | NOX1SMN1; SMN2KMT2AALDH1A1MAPT | |
| SCHEMBL10027944 | 0.69 | MAPT (0.42) | SMN1; SMN2L3MBTL1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102365020-B | Pyridazinone compounds | TAKEDA PHARMACEUTICAL | 2014-07-30 | — | — | CN | disclosed |
| EP-2393360-A1 | PYRIDAZINONE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2011-12-14 | — | — | EP | disclosed |
| WO-2010090737-A1 | PYRIDAZINONE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-12 | — | — | WO | disclosed |