Phosphocholine

Phosphocholine

SCHEMBL3713381

CCCCCCCC/C=C\CCCCCCCC(=O)O[C@@H](CO)C(O)C(=O)CCCCCCCCCCCCCCC.C[N+](C)(C)CCOP(=O)(O)O

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 1/20 0.53
LPAR1 Q92633 8/20 0.50
ALDH1A1 P00352 1/20 0.49
ENPP2 Q13822 4/20 0.49
LPAR2 Q9HBW0 3/20 0.49
LPAR3 Q9UBY5 3/20 0.49
LPAR4 Q99677 2/20 0.49
LPAR5 Q9H1C0 2/20 0.49
CES2 O00748 1/20 0.49
LPAR6 P43657 1/20 0.49
TRPV1 Q8NER1 1/20 0.49
FABP3 P05413 1/20 0.48
DAGLA Q9Y4D2 1/20 0.46
SELP P16109 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
NR5A2 O00482 1/20 0.45
NR5A1 Q13285 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL538239 0.92 FABP3 (0.52) S1PR1LPAR1ALDH1A1FABP3DAGLA
Phosphocholine SCHEMBL5087547 0.90 ALDH1A1 (0.56) S1PR1LPAR1ALDH1A1FABP3DAGLA
Phosphocholine SCHEMBL6534600 0.89 ALDH1A1 (0.58) S1PR1ALDH1A1FABP3SELPSMN1; SMN2
Phosphocholine SCHEMBL28007022 0.87 LPAR1 (0.50) S1PR1LPAR1ALDH1A1ENPP2LPAR2
Phosphocholine SCHEMBL9131205 0.87 LPAR1 (0.52) S1PR1LPAR1ALDH1A1ENPP2LPAR2
Phosphocholine SCHEMBL669518 0.87 S1PR1 (0.49) S1PR1LPAR1ALDH1A1ENPP2LPAR2
Phosphocholine SCHEMBL28832346 0.86 S1PR1 (0.53) S1PR1LPAR1ALDH1A1ENPP2LPAR2
Phosphocholine SCHEMBL28083428 0.86 S1PR1 (0.53) S1PR1LPAR1ALDH1A1ENPP2LPAR2
Phosphocholine SCHEMBL1557025 0.86 SMN1; SMN2 (0.53) LPAR1ALDH1A1LPAR2LPAR3LPAR4
Phosphocholine SCHEMBL28007296 0.86 S1PR1 (0.68) S1PR1LPAR1ALDH1A1ENPP2LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010096806-A1 METHODS FOR LOADING CONTRAST AGENTS INTO A LIPOSOME DUKE UNIVERSITY (US) 2010-08-26 WO disclosed