Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SELP | P16109 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | P2RY10 | O00398 | 4/20 | 0.46 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.46 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphocholine SCHEMBL3713381 | 0.92 | S1PR1 (0.53) | FABP3ALDH1A1SELPS1PR1DAGLA | |
| Phosphocholine SCHEMBL5087547 | 0.88 | ALDH1A1 (0.56) | FABP3ALDH1A1SELPS1PR1DAGLA | |
| Phosphocholine SCHEMBL6534600 | 0.87 | ALDH1A1 (0.58) | FABP3ALDH1A1SELPS1PR1SMN1; SMN2 | |
| SCHEMBL9053470 | 0.85 | FABP3 (0.52) | FABP3ALDH1A1SELPS1PR1P2RY10 | |
| Phosphocholine SCHEMBL1557025 | 0.84 | SMN1; SMN2 (0.53) | FABP3ALDH1A1LPAR1SMN1; SMN2 | |
| SCHEMBL776856 | 0.83 | FABP3 (0.72) | FABP3ALDH1A1SELPS1PR1P2RY10 | |
| SCHEMBL4964792 | 0.82 | PRKCA (0.59) | ALDH1A1S1PR1DAGLASLC6A5 | |
| SCHEMBL6252306 | 0.82 | PRKCA (0.59) | ALDH1A1S1PR1DAGLASLC6A5 | |
| SCHEMBL9055293 | 0.82 | PRKCA (0.59) | ALDH1A1S1PR1DAGLASLC6A5 | |
| SCHEMBL1666730 | 0.82 | PRKCA (0.59) | ALDH1A1S1PR1DAGLASLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2413951-A2 | FORMULATION FOR INDUCING BROADLY REACTIVE NEUTRALIZING ANTI-HIV ANTIBODIES | Duke University (US) | 2012-02-08 | — | — | EP | disclosed |
| EP-2413905-A2 | FORMULATION | Duke University (US) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010114628-A9 | FORMULATION FOR INDUCING BROADLY REACTIVE NEUTRALIZING ANTI-HIV ANTIBODIES | DUKE UNIVERSITY (US) | 2010-11-25 | — | — | WO | disclosed |
| WO-2010114629-A2 | FORMULATION | DUKE UNIVERSITY (US) | 2010-10-07 | — | — | WO | disclosed |
| WO-2010114628-A2 | FORMULATION FOR INDUCING BROADLY REACTIVE NEUTRALIZING ANTI-HIV ANTIBODIES | DUKE UNIVERSITY (US) | 2010-10-07 | — | — | WO | disclosed |