Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 11/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.35 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3104836 | 0.91 | CNR1 (0.56) | CNR1MAPTKMT2ACNR2TP53 | |
| SCHEMBL3110050 | 0.81 | CNR1 (0.60) | CNR1KMT2ACNR2TP53POLB | |
| SCHEMBL3113229 | 0.81 | CNR1 (0.55) | CNR1KMT2ACNR2 | |
| SCHEMBL3103553 | 0.78 | CNR1 (0.58) | CNR1MAPTKMT2A | |
| SCHEMBL3113188 | 0.77 | PPARD (0.44) | CNR1MAPTCNR2 | |
| SCHEMBL3114375 | 0.76 | CNR1 (0.58) | CNR1MAPTKMT2A | |
| SCHEMBL3224422 | 0.75 | CNR1 (0.52) | CNR1KMT2ACNR2 | |
| SCHEMBL3111589 | 0.71 | ROCK2 (0.36) | CNR1CNR2 | |
| SCHEMBL13307940 | 0.70 | CNR1 (1.00) | CNR1 | |
| SCHEMBL23135761 | 0.69 | KMT2A (0.62) | MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2209768-A1 | 5,6-DIARYL PYRIDINES SUBSTITUTED IN THE 2- AND 3-POSITION, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2010-07-28 | — | — | EP | disclosed |
| WO-2009087285-A1 | 5,6-DIARYL PYRIDINES SUBSTITUTED IN THE 2- AND 3-POSITION, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2009-07-16 | — | — | WO | disclosed |