Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | LDHB | P07195 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2122346 | 1.00 | RAB9A (0.44) | RAB9ANPC1CTDSP1KMT2ABACE1 | |
| SCHEMBL2122343 | 1.00 | RAB9A (0.44) | RAB9ANPC1CTDSP1KMT2ABACE1 | |
| SCHEMBL2568537 | 0.92 | KMT2A (0.43) | RAB9ANPC1CTDSP1KMT2ABACE1 | |
| SCHEMBL3714840 | 0.91 | SMN1; SMN2 (0.47) | RAB9ANPC1CTDSP1KMT2ABACE1 | |
| SCHEMBL2123046 | 0.91 | SMN1; SMN2 (0.47) | RAB9ANPC1CTDSP1KMT2ABACE1 | |
| SCHEMBL2123050 | 0.91 | SMN1; SMN2 (0.47) | RAB9ANPC1CTDSP1KMT2ABACE1 | |
| SCHEMBL2120036 | 0.90 | RAB9A (0.46) | RAB9ANPC1CTDSP1KMT2ABACE1 | |
| SCHEMBL479876 | 0.90 | RAB9A (0.46) | RAB9ANPC1CTDSP1KMT2ABACE1 | |
| SCHEMBL16752527 | 0.89 | BACE1 (0.54) | RAB9ANPC1CTDSP1KMT2ABACE1 | |
| SCHEMBL2121458 | 0.89 | BACE1 (0.54) | RAB9ANPC1CTDSP1KMT2ABACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010108665-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | LIFE & BRAIN GMBH (DE) | 2010-09-30 | — | — | WO | disclosed |