SCHEMBL3713883

SCHEMBL3713883

C=CCc1ccc2cccc3c2c1-c1ccccc1-3

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 7/20 0.45
▸ HSD17B10 Q99714 5/20 0.45
▸ MAPK1 P28482 4/20 0.45
▸ TSHR P16473 4/20 0.45
▸ ATM Q13315 2/20 0.45
▸ L3MBTL1 Q9Y468 2/20 0.45
▸ GABRA1 P14867 1/20 0.43
▸ GABRB2 P47870 1/20 0.43
▸ CASP1 P29466 3/20 0.38
▸ CASP7 P55210 2/20 0.38
▸ CYP3A4 P08684 2/20 0.38
▸ PABPC1 P11940 1/20 0.38
▸ DNMT1 P26358 1/20 0.38
▸ AKR1B1 P15121 1/20 0.38
▸ ELANE P08246 1/20 0.37
▸ HPGD P15428 4/20 0.37
▸ HIF1A Q16665 2/20 0.37
▸ TP53 P04637 1/20 0.37
▸ ANPEP P15144 1/20 0.34
▸ KDM4E B2RXH2 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1078566 0.78 GABRA1 (0.57) ALDH1A1MAPK1L3MBTL1GABRA1GABRB2
SCHEMBL9465662 0.77 HSD17B10 (0.50) ALDH1A1HSD17B10MAPK1TSHRATM
SCHEMBL11657069 0.77 ALDH1A1 (0.50) ALDH1A1HSD17B10MAPK1TSHRATM
SCHEMBL9466070 0.77 ALDH1A1 (0.50) ALDH1A1HSD17B10MAPK1TSHRATM
SCHEMBL8518060 0.77 PARP1 (0.53) ALDH1A1HSD17B10GABRA1GABRB2CASP1
SCHEMBL16042131 0.77 GABRA1 (0.43) ALDH1A1HSD17B10MAPK1TSHRL3MBTL1
SCHEMBL11690554 0.75 ALDH1A1 (0.47) ALDH1A1HSD17B10MAPK1TSHRATM
SCHEMBL13975762 0.74 PPARG (0.42) ALDH1A1HSD17B10MAPK1TSHRATM
SCHEMBL10588088 0.74 ALDH1A1 (0.50) ALDH1A1HSD17B10MAPK1TSHRATM
SCHEMBL27885410 0.73 ALDH1A1 (0.45) ALDH1A1HSD17B10MAPK1TSHRATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4016135-A STABILIZATION OF A POLYMERIC RESIN WITH AN ALKYL SUBSTITUTED TETRACYCLIC COMPOUND KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1977-04-05 — — US claimed
US-3985938-A Dielectric ethylene copolymer compositions containing alkylfluoranthene KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1976-10-12 — — US claimed
EP-2126934-B1 CABLE INSULATION WITH REDUDED ELECTRICAL TREEING UNION CARBIDE CHEM PLASTIC (US) 2015-09-23 — — EP disclosed
EP-2854139-A1 Cable insulation with reduced electrical treeing Union Carbide Chemicals & Plastics Technology LLC (US) 2015-04-01 — — EP disclosed
US-8680399-B2 Cable insulation with reduced electrical treeing UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY LLC (US) 2014-03-25 — — US disclosed
US-20100101823-A1 Cable Insulation with Reduced Electrical Treeing UNION CARBIDE CORPORATION 2010-04-29 — — US disclosed
CN-101675483-A Cable insulation with reduded electrical treeing UNION CARBIDE CHEM PLASTIC 2010-03-17 — — CN disclosed
EP-2126934-A2 CABLE INSULATION WITH REDUDED ELECTRICAL TREEING Union Carbide Chemicals & Plastics Technology LLC (US) 2009-12-02 — — EP disclosed
WO-2008112965-A2 CABLE INSULATION WITH REDUDED ELECTRICAL TREEING UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY LLC (US) 2008-09-18 — — WO disclosed
US-6879861-B2 Polymeric materials with improved dielectric breakdown strength MEDTRONIC, INC. (US) 2005-04-12 — — US disclosed
EP-1346375-A2 POLYMERIC MATERIALS WITH IMPROVED DIELECTRIC BREAKDOWN STRENGTH Medtronic, Inc. (US) 2003-09-24 — — EP disclosed
WO-2002059908-A2 POLYMERIC MATERIALS WITH IMPROVED DIELECTRIC BREAKDOWN STRENGTH MEDTRONIC, INC. (US) 2002-08-01 — — WO disclosed
US-20020082673-A1 Polymeric materials with improved dielectric breakdown strength MEDTRONIC, INC. 2002-06-27 — — US disclosed
US-4016135-A STABILIZATION OF A POLYMERIC RESIN WITH AN ALKYL SUBSTITUTED TETRACYCLIC COMPOUND KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1977-04-05 — — US disclosed
US-3985938-A Dielectric ethylene copolymer compositions containing alkylfluoranthene KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1976-10-12 — — US disclosed
US-3985938-A Dielectric ethylene copolymer compositions containing alkylfluoranthene KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1976-10-12 — — US disclosed
US-3985938-A Dielectric ethylene copolymer compositions containing alkylfluoranthene KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1976-10-12 — — US disclosed
US-3966674-A PROPYLFLUORANTHENE, PROPYLPYRENE KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1976-06-29 — — US disclosed
US-3966674-A PROPYLFLUORANTHENE, PROPYLPYRENE KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1976-06-29 — — US disclosed
US-3915945-A Dielectric polyolefin compositions KUREHA CHEMICAL IND CO LTD 1975-10-28 — — US disclosed
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