Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 11/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3716941 | 0.85 | FFAR1 (0.56) | ACACBFFAR1 | |
| SCHEMBL3713066 | 0.85 | ACACB (0.65) | ACACBFFAR1 | |
| SCHEMBL13187678 | 0.81 | KDM4D (0.47) | HTTSMN1; SMN2 | |
| SCHEMBL13188123 | 0.79 | KDM4D (0.43) | ACACBFFAR1 | |
| SCHEMBL3711749 | 0.79 | ACACB (0.46) | ACACBFFAR1SMN1; SMN2 | |
| SCHEMBL3711290 | 0.77 | FFAR1 (0.47) | ACACBFFAR1 | |
| SCHEMBL3714474 | 0.77 | SMPD1 (0.57) | ACACBFFAR1SMN1; SMN2 | |
| SCHEMBL13187834 | 0.74 | HDAC6 (0.42) | ACACBFFAR1 | |
| SCHEMBL13187782 | 0.72 | HDAC6 (0.46) | FFAR1 | |
| SCHEMBL9328434 | 0.70 | ACACB (0.54) | ACACBFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |