Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.45 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13188123 | 0.91 | KDM4D (0.43) | FFAR1EGLN1HDAC1HDAC6HDAC8 | |
| SCHEMBL13187686 | 0.84 | HDAC8 (0.54) | HDAC1HDAC6HDAC8KDM4DUSP30 | |
| SCHEMBL3714474 | 0.82 | SMPD1 (0.57) | FFAR1HDAC1SMPD1ACACB | |
| SCHEMBL3711389 | 0.82 | ACACB (0.58) | FFAR1EGLN1ACACB | |
| SCHEMBL3711749 | 0.80 | ACACB (0.46) | FFAR1HDAC1HDAC6HDAC8ACACB | |
| SCHEMBL3716655 | 0.79 | FFAR1 (0.45) | FFAR1HDAC1HDAC6HDAC8KDM4D | |
| SCHEMBL13187782 | 0.78 | HDAC6 (0.46) | FFAR1HDAC1HDAC6KDM4D | |
| SCHEMBL3713974 | 0.77 | ACACB (0.50) | FFAR1ACACB | |
| SCHEMBL3718292 | 0.76 | KMO (0.53) | FFAR1SLC16A3 | |
| SCHEMBL1202476 | 0.76 | KDM4E (0.52) | FFAR1EGLN1KDM4DSLC16A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |