Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.53 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.53 |
| ▸ | ACACB | O00763 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3712925 | 0.86 | ACACB (0.58) | PTPN1PTPN6PTPN11ACACBFFAR1 | |
| SCHEMBL13188123 | 0.85 | KDM4D (0.43) | PTPN11ACACBHDAC1FFAR1 | |
| SCHEMBL3715274 | 0.84 | SMPD1 (0.67) | SMPD1HDAC1 | |
| SCHEMBL3711290 | 0.82 | FFAR1 (0.47) | SMPD1ACACBHDAC1FFAR1 | |
| SCHEMBL3711749 | 0.81 | ACACB (0.46) | ACACBHDAC1FFAR1RAB9ANPC1 | |
| SCHEMBL3713974 | 0.77 | ACACB (0.50) | ACACBFFAR1SMN1; SMN2 | |
| SCHEMBL14786201 | 0.74 | MAOB (0.71) | PTPN1PTPN6PTPN11FFAR1RAB9A | |
| SCHEMBL3713068 | 0.72 | HDAC1 (0.82) | SMPD1HDAC1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4364752 | 0.72 | BRAF (0.62) | — | |
| SCHEMBL18681644 | 0.72 | CSF1R (0.54) | SMPD1NR4A2P4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |