Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GABBR2 | O75899 | 4/20 | 0.34 |
| ▸ | GABBR1 | Q9UBS5 | 4/20 | 0.34 |
| ▸ | BLM | P54132 | 3/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL371419 | 0.77 | BLM (0.43) | CYP1A2GABBR2GABBR1BLMDRD3 | |
| SCHEMBL864318 | 0.73 | CYP1A2 (0.47) | CYP1A2MEN1KMT2AGABBR2GABBR1 | |
| SCHEMBL371423 | 0.73 | GABBR2 (0.42) | CYP1A2MEN1KMT2AGABBR2GABBR1 | |
| SCHEMBL9203527 | 0.72 | ANPEP (0.40) | CYP1A2MEN1KMT2AGABBR2GABBR1 | |
| SCHEMBL9203703 | 0.71 | CYP1A2 (0.42) | CYP1A2MEN1KMT2AGABBR2GABBR1 | |
| SCHEMBL371407 | 0.71 | MEN1 (0.35) | CYP1A2MEN1KMT2ATSHRCYP3A4 | |
| SCHEMBL3175491 | 0.71 | LAP3 (0.43) | ANPEPFDPS | |
| SCHEMBL371460 | 0.70 | DRD3 (0.31) | CYP1A2MEN1KMT2ABLMDRD3 | |
| SCHEMBL5841650 | 0.70 | PLA2G2C (0.43) | CYP1A2MEN1KMT2AGABBR2GABBR1 | |
| SCHEMBL17782328 | 0.70 | PLA2G2C (0.43) | CYP1A2MEN1KMT2AGABBR2GABBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408790-A1 | METHODS FOR THE PREPARATION OF [2-(8,9-DIOXO-2,6-DIAZABICYCLO[5.2.0]NON-1(7)-EN-2-YL)ETHYL]PHOSPHONIC ACID AND PRECURSORS THEREOF | Wyeth LLC (US) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010108063-A1 | METHODS FOR THE PREPARATION OF [2-(8,9-DIOXO-2,6-DIAZABICYCLO[5.2.0]NON-1(7)-EN-2-YL)ETHYL]PHOSPHONIC ACID AND PRECURSORS THEREOF | WYETH LLC (US) | 2010-09-23 | — | — | WO | disclosed |