Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29696576 | 0.72 | ALDH1A1 (0.54) | TOP1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL5567841 | 0.69 | ALDH1A1 (0.46) | TOP1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL28741694 | 0.68 | ALDH1A1 (0.51) | TOP1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL521943 | 0.68 | ALDH1A1 (0.62) | TOP1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL745227 | 0.66 | ALDH1A1 (0.46) | TOP1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL28079025 | 0.63 | ALDH1A1 (0.49) | TOP1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL22733867 | 0.63 | ALDH1A1 (0.49) | TOP1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL18671634 | 0.62 | ALDH1A1 (0.51) | TOP1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL3087312 | 0.62 | ALDH1A1 (0.54) | TOP1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL28253382 | 0.61 | ESR1 (0.62) | ALDH1A1KDM4EHPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077589-A2 | STAT3 INHIBITORS AND THERAPEUTIC METHODS USING THE SAME | THE REGENTS OF THE UNIVERSITY OF MICHIGAN OFFICE OF TECHNOLOGY TRANSFER (US) | 2010-07-08 | — | — | WO | disclosed |