Pentane

Pentane

SCHEMBL3714433

CC(C)CCOCCC(C)C.CCCCC

nearest known ligand 0.40

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.40
LMNA P02545 2/20 0.39
ALDH1A1 P00352 1/20 0.39
OPRM1 P35372 1/20 0.36
MEN1 O00255 1/20 0.36
THRB P10828 1/20 0.36
HTT P42858 1/20 0.36
KMT2A Q03164 1/20 0.36
MAPT P10636 1/20 0.36
CYP3A4 P08684 2/20 0.34
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
HSD17B10 Q99714 1/20 0.33
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
ADRB3 P13945 1/20 0.33
DNM1 Q05193 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pentane SCHEMBL27648255 0.93 HTT (0.46) TSHROPRM1MEN1THRBHTT
SCHEMBL9622598 0.92 TSHR (0.50) TSHRALDH1A1OPRM1MEN1THRB
SCHEMBL128468 0.92 TSHR (0.50) TSHRALDH1A1OPRM1MEN1THRB
SCHEMBL10498249 0.90 TSHR (0.48) TSHRALDH1A1OPRM1MEN1THRB
SCHEMBL1150476 0.90 HTT (0.48) TSHRALDH1A1OPRM1MEN1THRB
SCHEMBL23945735 0.90 TSHR (0.48) TSHRALDH1A1OPRM1MEN1THRB
SCHEMBL29320747 0.90 TSHR (0.48) TSHRALDH1A1OPRM1MEN1THRB
SCHEMBL29320743 0.90 TSHR (0.48) TSHRALDH1A1OPRM1MEN1THRB
SCHEMBL10498292 0.90 TSHR (0.48) TSHRALDH1A1OPRM1MEN1THRB
Butane SCHEMBL2850670 0.88 ALDH1A1 (0.42) TSHRLMNAALDH1A1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010144080-A1 IMPROVED CATALYST FLOW BASF CATALYSTS LLC (US) 2010-12-16 WO disclosed
US-7638585-B2 Catalyst flow BASF CATALYSTS, LLC (US) 2009-12-29 US disclosed
US-20090286942-A1 CATALYST FLOW BASF CATALYSTS LLC (US) 2009-11-19 US disclosed
US-7135531-B2 Spherical catalyst for olefin polymerization BASF CATALYSTS LLC (US) 2006-11-14 US disclosed
US-20050176900-A1 Spherical catalyst for olefin polymerization ENGELHARD CORPORATION 2005-08-11 US disclosed