SCHEMBL128468

SCHEMBL128468

CCCCOCCC(C)C

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
CYP3A4 P08684 2/20 0.43
MAPT P10636 2/20 0.39
MEN1 O00255 1/20 0.39
THRB P10828 1/20 0.39
HTT P42858 1/20 0.39
KMT2A Q03164 1/20 0.39
ADRB2 P07550 1/20 0.38
ADRB1 P08588 1/20 0.38
ADRB3 P13945 1/20 0.38
ALDH1A1 P00352 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
HPGD P15428 1/20 0.37
GBA2 Q9HCG7 2/20 0.35
HSD17B10 Q99714 1/20 0.35
GBA1 P04062 1/20 0.35
OPRM1 P35372 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
USP2 O75604 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9622598 1.00 TSHR (0.50) TSHRCYP3A4MAPTMEN1THRB
SCHEMBL29320743 0.97 TSHR (0.48) TSHRCYP3A4MAPTMEN1THRB
SCHEMBL10498249 0.97 TSHR (0.48) TSHRCYP3A4MAPTMEN1THRB
SCHEMBL10498292 0.97 TSHR (0.48) TSHRCYP3A4MAPTMEN1THRB
SCHEMBL29320747 0.97 TSHR (0.48) TSHRCYP3A4MAPTMEN1THRB
SCHEMBL23945735 0.97 TSHR (0.48) TSHRCYP3A4MAPTMEN1THRB
SCHEMBL1150476 0.92 HTT (0.48) TSHRMAPTMEN1THRBHTT
Pentane SCHEMBL3714433 0.92 TSHR (0.40) TSHRCYP3A4MAPTMEN1THRB
Ethylene Glycol SCHEMBL10498287 0.91 TSHR (0.60) TSHRCYP3A4MAPTMEN1THRB
SCHEMBL23854124 0.90 HTT (0.52) TSHRMAPTMEN1THRBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4074739-A1 TREATMENT LIQUID AND PATTERN FORMING METHOD FUJIFILM Corporation (JP) 2022-10-19 EP claimed
US-20220308449-A1 TREATMENT LIQUID AND PATTERN FORMING METHOD FUJIFILM CORPORATION (JP) 2022-09-29 US claimed
CN-114787717-A Processing liquid and pattern forming method 富士胶片株式会社 2022-07-22 CN claimed
WO-2021117456-A1 TREATMENT LIQUID AND PATTERN FORMING METHOD 富士フイルム株式会社 2021-06-17 WO claimed
EP-0068799-A2 Titanium trichloride catalyst component and the process for the production thereof EXXON RESEARCH AND ENGINEERING COMPANY (US) 1983-01-05 EP claimed
US-20240238458-A1 COMPOUNDS TARGETING FIBROBLAST-ACTIVATION PROTEIN AND METHODS OF USE THEREOF PURDUE RESEARCH FOUNDATION 2024-07-18 US disclosed
EP-3604983-B1 METHOD FOR DETECTING LOCATION OF REFRIGERANT LEAK DAIKIN IND LTD (JP) 2024-07-17 EP disclosed
US-20240226343-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. 2024-07-11 US disclosed
CN-117924548-A Catalyst component for olefin polymerization, preparation method, catalyst system and olefin polymerization method 中国石油化工股份有限公司 2024-04-26 CN disclosed
US-11873291-B2 Quinoline cGAS antagonist compounds IMMUNESENSOR THERAPEUTICS, INC. (US) 2024-01-16 US disclosed
US-20230357158-A1 QUINOLINE cGAS ANTAGONIST COMPOUNDS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2023-11-09 US disclosed
WO-2023171326-A1 METHOD FOR PRODUCING ALKENE 株式会社クレハ 2023-09-14 WO disclosed
EP-0021822-A1 Titanium trichloride catalytic component and method for homo- or co-polymerization of alpha-olefins TOYO STAUFFER CHEMICAL CO. LTD. (JP) 1981-01-07 EP disclosed
US-4240928-A FOR POLYMERIZATION OF ALPHA-OLEFINS TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1980-12-23 US disclosed
US-4235745-A FOR PREPARING HIGHLY STEREOSPECIFIC POLYMERS TOYO STAUFFER CHEMICAL CO., LTD. (JP) 1980-11-25 US disclosed
EP-0011914-A1 Titanium trichloride catalyst composition and its use in the polymerization of alpha-olefins EXXON RESEARCH AND ENGINEERING COMPANY (US) 1980-06-11 EP disclosed
US-4200717-A Preparation of propylene polymer-containing solid titanium trichloride and propylene polymers using same MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) 1980-04-29 US disclosed
US-4115533-A REDUCING TITANIUM TETRACHLORIDE WITH AN ORGANIC ALUMINUM COMPOUND MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) 1978-09-19 US disclosed
US-4115532-A LEWIS ACIDS, HEATING, PRECIPITATION MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) 1978-09-19 US disclosed
US-4060593-A Preparation of titanium trichloride MITSUBISHI CHEMICAL INDUSTRIES (JA) 1977-11-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11873291-B2 Quinoline cGAS antagonist compounds CGAS, GLS2, GLS TSHR 2355/4885CYP3A4 1291/4885MAPT 3235/4885
US-20240238458-A1 COMPOUNDS TARGETING FIBROBLAST-ACTIVATION PROTEIN AND METHODS OF USE THEREOF FAP, FIBP, FGFR1 TSHR 4225/4885CYP3A4 4676/4885MAPT 3208/4885
US-20230357158-A1 QUINOLINE cGAS ANTAGONIST COMPOUNDS CGAS, GLS2, GLS TSHR 2355/4885CYP3A4 1291/4885MAPT 3235/4885
US-20240226343-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF NPY1R, NPY2R, NPY4R TSHR 76/4885CYP3A4 4773/4885MAPT 2444/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.