Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.52 |
| ▸ | ENPEP | Q07075 | 4/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.37 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LAP3 | P28838 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1428936 | 1.00 | KDM4E (0.52) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Hydrochloric Acid SCHEMBL1574245 | 0.98 | ACE (0.50) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Hydrochloric Acid SCHEMBL19332925 | 0.98 | ACE (0.50) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL1058215 | 0.82 | KDM4E (0.56) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL25761663 | 0.82 | KDM4E (0.56) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL1058214 | 0.82 | KDM4E (0.56) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL28854052 | 0.82 | KDM4E (0.56) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL1934656 | 0.80 | TGFBR1 (0.52) | FOLH1SLC7A5NAALAD2TGFBR1ALDH1A1 | |
| SCHEMBL28581576 | 0.80 | TGFBR1 (0.52) | FOLH1SLC7A5NAALAD2TGFBR1ALDH1A1 | |
| SCHEMBL23552453 | 0.80 | KDM4E (0.54) | KDM4EMAPTTHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359560-B1 | MULTIRESIDUAL METHOD FOR DETECTING AND/OR QUANTIFYING AMINO ACIDS, ORGANIC ACIDS AND/OR MODIFIED NUCLEOTIDES BY MEANS OF HILIC CHROMATOGRAPHIC SEPARATION AND MS/MS | CRESCENDO CARE S R L (IT) | 2025-05-07 | — | — | EP | claimed |
| US-20240288409-A1 | MULTIRESIDUAL METHOD FOR DETECTING AND/OR QUANTIFYING AMINO ACIDS, ORGANIC ACIDS AND/OR MODIFIED NUCLEOTIDES BY MEANS OF HILIC CHROMATOGRAPHIC SEPARATION AND MS/MS | CRESCENDO CARE S.R.L. (IT) | 2024-08-29 | — | — | US | claimed |
| CN-117897500-A | Multi-residue method for detecting and/or quantifying amino acids, organic acids and/or modified nucleotides by affinity chromatography and MS/MS | 渐进护理有限责任公司 | 2024-04-16 | — | — | CN | claimed |
| EP-4237427-A1 | ANTIBACTERIAL CYCLOPEPTIDES TARGETING ACINETOBACTER AND OTHER GRAM-NEGATIVE PATHOGENS | University of Utah Research Foundation (US) | 2023-09-06 | — | — | EP | claimed |
| CN-116670151-A | Antibacterial cyclic peptides targeting acinetobacter and other gram negative pathogens | 犹他大学研究基金会 | 2023-08-29 | — | — | CN | claimed |
| WO-2022094273-A1 | ANTIBACTERIAL CYCLOPEPTIDES TARGETING ACINETOBACTER AND OTHER GRAM-NEGATIVE PATHOGENS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2022-05-05 | — | — | WO | claimed |
| US-11084836-B2 | Compositions useful in therapy of autophagy-related pathologies, and methods of making and using the same | THE UNIVERSITY OF TOLEDO (US) | 2021-08-10 | — | — | US | claimed |
| US-20190270786-A1 | PEPTIDE INHIBITORS OF INTERLEUKIN-23 AND THEIR USE TO TREAT INFLAMMATORY DISEASES | PROTAGONIST THERAPEUTICS, INC. | 2019-09-05 | — | — | US | claimed |
| WO-2018022937-A1 | PEPTIDE INHIBITORS OF INTERLEUKIN-23 AND THEIR USE TO TREAT INFLAMMATORY DISEASES | PROTAGONIST THERAPEUTICS, INC. (US) | 2018-02-01 | — | — | WO | claimed |
| CN-106442758-A | Liquid mass spectrometry method for detecting various amino acids in human blood plasma in underivatized mode | 陈大为 | 2017-02-22 | — | — | CN | claimed |
| EP-1412515-A2 | TREATMENT OF CNS DISORDERS USING D-AMINO ACID OXIDASE AND D-ASPARTATE OXIDASE ANTAGONISTS | Genset (FR) | 2004-04-28 | — | — | EP | claimed |
| WO-2002066672-A2 | TREATMENT OF CNS DISORDERS USING D-AMINO ACID OXIDASE AND D-ASPARTATE OXIDASE ANTAGONISTS | GENSET S.A. (FR) | 2002-08-29 | — | — | WO | claimed |
| US-20020046973-A1 | Computerized method and apparatus for analyzing amino acids | HITACHI, LTD. (JP) | 2002-04-25 | — | — | US | claimed |
| US-6297054-B1 | RECOMBINANT CHIMERIC DNA CONSTRUCT FOR SELECTION OF TRANSFORMED PLASTIDS; INCLUDES EDITED PLASTID GENE FUSED TO CODING REGION OF SELECTABLE MARKER | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2001-10-02 | — | — | US | claimed |
| US-6018103-A | A CHIMERIC GENE COMPRISING OF SMALL NUCLEAR RNA OR MESSENGER RNA PROMOTER SPECIFIC FOR RNA POLYMERASE II AND SMALL NUCLEAR RNA TERMINATION ELEMENT FROM PLANTS; BOTH ELEMENTS FUNCTION INDEPENDENT OF THE OTHER; EXPRESSING CHIMERIC GENES IN PLANTS | NOVARTIS FINANCE CORPORATION (US) | 2000-01-25 | — | — | US | claimed |
| EP-0703987-A1 | CHIMERIC PLANT GENES POSSESSING INDEPENDENT REGULATORY SEQUENCES | Novartis AG (CH) | 1996-04-03 | — | — | EP | claimed |
| WO-1995000652-A1 | CHIMERIC PLANT GENES POSSESSING INDEPENDENT REGULATORY SEQUENCES | CIBA-GEIGY AG (CH) | 1995-01-05 | — | — | WO | claimed |
| US-5316930-A | DNA molecules and plant or bacteria cells | PIONEER HI-BRED INTERNATIONAL, INC. (US) | 1994-05-31 | — | — | US | claimed |
| EP-0240332-A2 | Virus resistant plants having antisense RNA | PIONEER HI-BRED INTERNATIONAL, INC. (US) | 1987-10-07 | — | — | EP | claimed |
| EP-0240331-A2 | Virus resistant plants having a viral coat protein | PIONEER HI-BRED INTERNATIONAL, INC. (US) | 1987-10-07 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190270786-A1 | PEPTIDE INHIBITORS OF INTERLEUKIN-23 AND THEIR USE TO TREAT INFLAMMATORY DISEASES | IL23R, IL17A, VIP | KDM4E 4540/4885MAPT 1474/4885THRB 3200/4885 |
| US-11084836-B2 | Compositions useful in therapy of autophagy-related pathologies, and methods of making and using the same | TFEB, SQSTM1, BECN1 | KDM4E 235/4885MAPT 215/4885THRB 2653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.