Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.66 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.66 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.66 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.61 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.55 |
| ▸ | ABL1 | P00519 | 2/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | KMO | O15229 | 1/20 | 0.54 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.54 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | BCR | P11274 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29771391 | 1.00 | ALDH1A1 (0.68) | ALDH1A1CYP11B1CYP11B2CYP19A1SLC2A1 | |
| SCHEMBL31704881 | 1.00 | ALDH1A1 (0.68) | ALDH1A1CYP11B1CYP11B2CYP19A1SLC2A1 | |
| SCHEMBL31705350 | 1.00 | ALDH1A1 (0.68) | ALDH1A1CYP11B1CYP11B2CYP19A1SLC2A1 | |
| SCHEMBL10028685 | 0.98 | ALDH1A1 (0.66) | ALDH1A1CYP11B1CYP11B2CYP19A1SLC2A1 | |
| SCHEMBL13188366 | 0.97 | CYP11B1 (0.67) | ALDH1A1CYP11B1CYP11B2CYP19A1SLC2A1 | |
| SCHEMBL13044192 | 0.92 | CYP11B1 (0.64) | ALDH1A1CYP11B1CYP11B2CYP19A1SLC2A1 | |
| SCHEMBL10028698 | 0.89 | CYP19A1 (0.68) | ALDH1A1CYP11B1CYP11B2CYP19A1SLC2A1 | |
| SCHEMBL3511516 | 0.89 | CYP19A1 (0.68) | ALDH1A1CYP11B1CYP11B2CYP19A1SLC2A1 | |
| SCHEMBL1399775 | 0.88 | CYP19A1 (0.74) | ALDH1A1CYP11B1CYP11B2CYP19A1SLC2A1 | |
| SCHEMBL9008962 | 0.87 | CYP11B1 (0.61) | ALDH1A1CYP11B1CYP11B2CYP19A1NEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002346-A1 | NEW COMPOUNDS AND METHODS | BenevolentAl Bio Limited (GB) | 2023-01-05 | — | — | US | disclosed |
| US-20230002346-A1 | NEW COMPOUNDS AND METHODS | BenevolentAl Bio Limited (GB) | 2023-01-05 | — | — | US | disclosed |
| EP-4028387-A1 | NEW COMPOUNDS AND METHODS | BenevolentAI Bio Limited (GB) | 2022-07-20 | — | — | EP | disclosed |
| CN-114502544-A | Novel compounds and methods | 博善人工智能生物科技有限公司 | 2022-05-13 | — | — | CN | disclosed |
| WO-2021048567-A1 | NEW COMPOUNDS AND METHODS | BENEVOLENTAI BIO LIMITED (GB) | 2021-03-18 | — | — | WO | disclosed |
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002346-A1 | NEW COMPOUNDS AND METHODS | ABL2, ABL1, ALK | ALDH1A1 651/4885CYP11B1 184/4885CYP11B2 209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.