SCHEMBL3714899

SCHEMBL3714899

OCCOc1c(Br)cc(-c2cc(Br)c(OCCO)c(Br)c2)cc1Br

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KLK1 P06870 1/20 0.46
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
THRB P10828 8/20 0.44
THRA P10827 7/20 0.44
MCHR1 Q99705 1/20 0.43
HRH3 Q9Y5N1 3/20 0.39
ALDH1A1 P00352 1/20 0.38
RECQL P46063 1/20 0.38
APEX1 P27695 1/20 0.38
APP P05067 1/20 0.37
SLC6A4 P31645 1/20 0.34
KDM4E B2RXH2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6285005 0.88 MEN1 (0.55) KLK1MEN1KMT2ATHRBTHRA
SCHEMBL7180070 0.85 KDM4E (0.48) KLK1MEN1KMT2ATHRBTHRA
SCHEMBL11647776 0.85 MEN1 (0.42) KLK1MEN1KMT2ATHRBTHRA
SCHEMBL6831640 0.85 THRB (0.45) KLK1MEN1KMT2ATHRBTHRA
SCHEMBL12908655 0.81 THRB (0.50) KLK1MEN1KMT2ATHRBTHRA
SCHEMBL31084168 0.80 ALDH1A1 (0.47) KLK1MEN1KMT2ATHRBTHRA
SCHEMBL28666067 0.80 MEN1 (0.42) KLK1MEN1KMT2ATHRBTHRA
SCHEMBL483839 0.80 MCHR1 (0.43) KLK1MEN1KMT2ATHRBTHRA
SCHEMBL11022560 0.80 MCHR1 (0.43) KLK1MEN1KMT2ATHRBTHRA
SCHEMBL28702768 0.80 MEN1 (0.42) KLK1MEN1KMT2ATHRBTHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250034071-A1 (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-01-30 US disclosed
US-20250019332-A1 (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS REUTER CHEMISCHE APPBAU E K (DE) 2025-01-16 US disclosed
EP-3508538-A1 INK-JET INK COMPOSITION AND IMAGE FORMATION METHOD FUJIFILM Corporation (JP) 2019-07-10 EP disclosed
US-20100199491-A1 MANUFACTURING METHOD OF IMAGE PICK-UP DEVICE, IMAGE PICK-UP DEVICE AND OPTICAL ELEMENT KONICA MINOLTA OPTO, INC. (JP) 2010-08-12 US disclosed
EP-2166395-A1 IMAGING DEVICE MANUFACTURING METHOD, IMAGING DEVICE AND OPTICAL ELEMENT Konica Minolta Opto, Inc. (JP) 2010-03-24 EP disclosed
US-6740721-B2 HAVING LOW VISCOSITY AND CAPABLE OF YIELDING A CURED MATERIAL HAVING A HIGH REFRACTIVE INDEX AND SMALL SPECIFIC GRAVITY SHOWA DENKO K.K. (JP) 2004-05-25 US disclosed
US-20030149141-A1 Plastic lens composition, plastic lens,and process for producing the plastic lens SHOWA DENKO K.K. (JP) 2003-08-07 US disclosed
EP-0691360-A2 Flame-retardant polyester resin and composition for injection molding POLYPLASTICS CO. LTD. (JP) 1996-01-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250019332-A1 (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS CBR1, CBR3, CBX2 KLK1 4466/4885MEN1 4579/4885KMT2A 926/4885
US-20250034071-A1 (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS CBR1, CBR3, AHR KLK1 4461/4885MEN1 4344/4885KMT2A 956/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.