Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | MMP13 | P45452 | 6/20 | 0.53 |
| ▸ | MMP2 | P08253 | 5/20 | 0.53 |
| ▸ | MMP8 | P22894 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13187814 | 0.93 | HDAC1 (0.61) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL3714232 | 0.85 | HDAC1 (0.54) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL3715159 | 0.85 | HDAC1 (0.65) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL3716532 | 0.82 | LMNA (0.54) | HDAC1ALDH1A1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL13188497 | 0.82 | MMP2 (0.52) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL13188523 | 0.81 | HDAC1 (0.55) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL31554953 | 0.81 | HRH3 (0.60) | HDAC1NPC1ALDH1A1TP53RAB9A | |
| SCHEMBL3719688 | 0.79 | HRH3 (0.59) | HDAC1NPC1ALDH1A1TP53RAB9A | |
| SCHEMBL3712338 | 0.79 | MMP2 (0.51) | MMP13MMP2MMP8MMP9 | |
| SCHEMBL3714253 | 0.79 | HDAC1 (0.52) | HDAC1HDAC3HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |